U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 171 - 180 of 9041 results

Status:
Investigational
Source:
INN:flavodic acid [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Flavodic acid is a synthetic hydrosoluble derivative of natural flavonoids. It has been shown to reduce capiliary fragility and permeability. Sodium flavodate was marketed by the Italian pharmaceutical company Farmaceutici under tradename Pericel.
Status:
Investigational
Source:
INN:diprogulic acid [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Diprogulic acid (Dikegulac) is used as a precursor in vitamin C synthesis. It is plant growth regulator for hedges. Dikegulac is used to differentially kill terminal apices, and it analogously inhibits basic metabolic functions in dividing cells, but not stationary cells, in suspension culture. At the lowest concentrations, dikegulac partially suppresses division of the isolated tobacco protoplasts. Higher concentrations are required to produce visual cytoplasmic damage to the protoplasts, which probably first occurs at the level of the plasmalemma, as the vacuoles can be released intact. Later, tonoplast disruption occurs. It does not inhibit mature leaves.
Status:
Investigational
Source:
INN:hydroxytoluic acid
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Hydroxytoluic acid is a long-acting derivative of salicylate with antilipidemic properties. It shows fibrinolytic activity in human plasma by activating the fibrinolytic system and has been shown to lower plasma free fatty acid, cholesterol levels, and to raise metabolic oxygen consumption.
Status:
Investigational
Source:
INN:clorindanic acid [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Clorindanic acid is a choleretic indanol derivative. Sterling Drug Inc. patented the compound in the 1960s. The compound is claimed to cause an increase in the rate of bile flow when administered to dogs. In rats, clorindanic acid was shown to have mild analgesic activity and hyperthermic effect.
Status:
Investigational
Source:
INN:clofenamic acid
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Clofenamic acid is a derivative of anthranilic acid, discovered by Parke-Davis. It possesses anti-inflammatory activity in the carrageenan-induced rat foot edema test.
Status:
Investigational
Source:
INN:tizoprolic acid [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Tizoprolic acid is an anti-lipolytic drug, a blood ketone lowering agent.
Status:
Investigational
Source:
INN:nixylic acid
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Nixylic acid, an anilinonicotinic acid derivative, is an anti-inflammatory agent.
Status:
Investigational
Source:
INN:xanoxic acid
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Xanoxic acid was developed as a bronchodilator that has never been marketed. Information about the current use of this agent is not available.
Status:
Investigational
Source:
INN:iotranic acid
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Iotranic Acid is triiodobenzoic acid derivative with potential application as new cholangiographic contrast media for liver imaging
Status:
Investigational
Source:
INN:ioxotrizoic acid
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Ioxotrizoic acid is acylated 3,5-diaminopolyhalobenzoic acid derivative patented by Sterling Drug Inc. as X-ray contrast agent for liver and spleen.