FLAVODIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H14O8
Molecular Weight	370.3097
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)COC1=CC(OCC(O)=O)=C2C(=O)C=C(OC2=C1)C3=CC=CC=C3

InChI

InChIKey=IGCSSLDDCHLXGL-UHFFFAOYSA-N

InChI=1S/C19H14O8/c20-13-8-14(11-4-2-1-3-5-11)27-16-7-12(25-9-17(21)22)6-15(19(13)16)26-10-18(23)24/h1-8H,9-10H2,(H,21,22)(H,23,24)

HIDE SMILES / InChI

Molecular Formula	C19H14O8
Molecular Weight	370.3097
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/27048768 | https://www.ncbi.nlm.nih.gov/pubmed/7107758

Flavodic acid is a synthetic hydrosoluble derivative of natural flavonoids. It has been shown to reduce capiliary fragility and permeability. Sodium flavodate was marketed by the Italian pharmaceutical company Farmaceutici under tradename Pericel.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
negative regulation of neutrophil degranulation 2 Target ID: GO:0043314 Sources: https://www.ncbi.nlm.nih.gov/pubmed/11759181	Modulator 828

PubMed

Title	Date	PubMed
Determination of sodium flavodate in body fluids by high-performance liquid chromatography: application to clinical pharmacokinetic studies.	1982 Jun 11	7107758
Phlebotonics for venous insufficiency.	2005 Jul 20	16034893
Phlebotonics for venous insufficiency.	2016 Apr 6	27048768

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:22:29 UTC 2023` Edited by `admin` on `Fri Dec 15 16:22:29 UTC 2023`
Record UNII	2Z9V171UEM
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FLAVODIC ACID

Official Name

English

Flavodic acid [WHO-DD]

Common Name

English

((4-OXO-2-PHENYL-4H-1-BENZOPYRAN-5,7-DIYL)DIOXY)DIACETIC ACID

Systematic Name

English

flavodic acid [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1745