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Details

Stereochemistry ABSOLUTE
Molecular Formula C13H11N3O4S
Molecular Weight 305.309
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of BLI-489 FREE ACID

SMILES

[H][C@]12SC=C(N1C(=O)\C2=C\C3=CN4CCOCC4=N3)C(O)=O

InChI

InChIKey=DMEYZPJEFHGESJ-CPWLGJMPSA-N
InChI=1S/C13H11N3O4S/c17-11-8(12-16(11)9(6-21-12)13(18)19)3-7-4-15-1-2-20-5-10(15)14-7/h3-4,6,12H,1-2,5H2,(H,18,19)/b8-3-/t12-/m1/s1

HIDE SMILES / InChI

Description

BLI 489 was developed by Wyeth as a 6-methylidene-penem β-lactamase inhibitor for the treatment of bacterial infections and urinary tract infections. BLI-489 has shown the promising clinical data, however, development of this drug, was discontinued.

Originator

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Intravenous
Name Type Language
BLI-489 FREE ACID
Common Name English
BLI 489 FREE ACID
Common Name English
4-THIA-1-AZABICYCLO(3.2.0)HEPT-2-ENE-2-CARBOXYLIC ACID, 6-((5,6-DIHYDRO-8H-IMIDAZO(2,1-C)(1,4)OXAZIN-2-YL)METHYLENE)-7-OXO-, (5R,6Z)-
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID60212945
Created by admin on Fri Dec 15 16:23:40 GMT 2023 , Edited by admin on Fri Dec 15 16:23:40 GMT 2023
PRIMARY
PUBCHEM
9972353
Created by admin on Fri Dec 15 16:23:40 GMT 2023 , Edited by admin on Fri Dec 15 16:23:40 GMT 2023
PRIMARY
CAS
635322-76-8
Created by admin on Fri Dec 15 16:23:40 GMT 2023 , Edited by admin on Fri Dec 15 16:23:40 GMT 2023
PRIMARY
FDA UNII
156B510BCG
Created by admin on Fri Dec 15 16:23:40 GMT 2023 , Edited by admin on Fri Dec 15 16:23:40 GMT 2023
PRIMARY
SALT/SOLVATE (PARENT)
Structure of BLI-489
NIH
NCATS
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