FLAVODIC ACID

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H14O8
Molecular Weight	370.3097
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FLAVODIC ACID

Structure Search

SMILES

OC(=O)COC1=CC2=C(C(=O)C=C(O2)C3=CC=CC=C3)C(OCC(O)=O)=C1

InChI

InChIKey=IGCSSLDDCHLXGL-UHFFFAOYSA-N

InChI=1S/C19H14O8/c20-13-8-14(11-4-2-1-3-5-11)27-16-7-12(25-9-17(21)22)6-15(19(13)16)26-10-18(23)24/h1-8H,9-10H2,(H,21,22)(H,23,24)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/27048768 | https://www.ncbi.nlm.nih.gov/pubmed/7107758

Flavodic acid is a synthetic hydrosoluble derivative of natural flavonoids. It has been shown to reduce capiliary fragility and permeability. Sodium flavodate was marketed by the Italian pharmaceutical company Farmaceutici under tradename Pericel.

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
negative regulation of neutrophil degranulation 2 Target ID: GO:0043314 Sources: https://www.ncbi.nlm.nih.gov/pubmed/11759181	Modulator 846

PubMed

PubMed

Title	Date	PubMed
Phlebotonics for venous insufficiency.	2016-04-06	27048768
Phlebotonics for venous insufficiency.	2005-07-20	16034893
Determination of sodium flavodate in body fluids by high-performance liquid chromatography: application to clinical pharmacokinetic studies.	1982-06-11	7107758

Name

Type

Language

FLAVODIC ACID

Official Name

English

Flavodic acid [WHO-DD]

Preferred Name

English

((4-OXO-2-PHENYL-4H-1-BENZOPYRAN-5,7-DIYL)DIOXY)DIACETIC ACID

Systematic Name

English

flavodic acid [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1745

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Code System Code Type Description

DRUG CENTRAL

1173

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NCI_THESAURUS

C65690

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INN

2680

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MESH

C002094

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ChEMBL

CHEMBL2107394

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EPA CompTox

DTXSID90190909

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SMS_ID

100000080989

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RXCUI

25060

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RxNorm

PUBCHEM

71944

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EVMPD

SUB07633MIG

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FDA UNII

2Z9V171UEM

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CAS

37470-13-6

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ECHA (EC/EINECS)

253-517-0

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ACTIVE MOIETY


					2Z9V171UEM

SALT/SOLVATE (PARENT)


					S560D4J29E

FLAVODATE DISODIUM