U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 158451 - 158460 of 167129 results

Status:
US Previously Marketed
Source:
Roniacol by Hoffmann-La Roche
(1949)
Source URL:
First approved in 1949
Source:
Roniacol by Hoffmann-La Roche
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)


Nicotinyl alcohol is a direct-acting vasolidator, that may decrease the blood pressure and it is a cholesterol-lowering agent. Nicotinyl alcohol as a tartrate salt led to the efficiency improvements in patients with intermittent claudication. In addition, nicotinyl alcohol alone or associated with other drugs was studied in the treatment of radicular syndromes; and was shown, that the effect had not been due to mechanical compression.
Status:
US Previously Marketed
Source:
Pyrrolazote by Upjohn
(1949)
Source URL:
First approved in 1949
Source:
Pyrrolazote by Upjohn
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

PARATHIAZINE, a member of phenothiazines, is a histamine receptor antagonist used for the treatment of allergic diseases. Also, it can be used as an antiemetic agent.
Status:
US Previously Marketed
Source:
Roniacol by Hoffmann-La Roche
(1949)
Source URL:
First approved in 1949
Source:
Roniacol by Hoffmann-La Roche
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Nicotinyl alcohol is a direct-acting vasolidator, that may decrease the blood pressure and it is a cholesterol-lowering agent. Nicotinyl alcohol as a tartrate salt led to the efficiency improvements in patients with intermittent claudication. In addition, nicotinyl alcohol alone or associated with other drugs was studied in the treatment of radicular syndromes; and was shown, that the effect had not been due to mechanical compression.
Status:
US Previously Marketed
Source:
Thiomerin Sodium by Campbell (Ayerst)
(1949)
Source URL:
First approved in 1949
Source:
Thiomerin Sodium by Campbell (Ayerst)
Source URL:

Class (Stereo):
CHEMICAL (MIXED)


MERCAPTOMERIN is a mercurial diuretic used for the treatment of congestive heart failure. It is an effective diuretic not only when given intramuscularly and intravenously but also when given subcutaneously.
Status:
US Previously Marketed
First approved in 1949

Class (Stereo):
CHEMICAL (ABSOLUTE)



Metocurine, also known as dimethyltubocurarine, is a non-depolarizing muscle relaxant through the neuromuscular blockade. It antagonizes the neurotransmitter action of acetylcholine by binding competitively with cholinergic receptor sites on the motor end-plate. Patients chronically receiving anticonvulsants are relatively resistant to metocurine.
Status:
US Previously Marketed
First approved in 1949

Class (Stereo):
CHEMICAL (ABSOLUTE)



Metocurine, also known as dimethyltubocurarine, is a non-depolarizing muscle relaxant through the neuromuscular blockade. It antagonizes the neurotransmitter action of acetylcholine by binding competitively with cholinergic receptor sites on the motor end-plate. Patients chronically receiving anticonvulsants are relatively resistant to metocurine.
Status:
US Previously Marketed
Source:
Panparnit HCl by Geigy
(1949)
Source URL:
First approved in 1949
Source:
Panparnit HCl by Geigy
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Caramiphen is a muscarinic M1 acetylcholine receptor antagonist, which was used for the treatment of Parkinson Disease and cough, but then there using were discontinued. Caramiphen is also used in local anesthesia, and effect could be achieved through the suppression of voltage-gated Na⁺ currents.
Status:
US Previously Marketed
Source:
Panparnit HCl by Geigy
(1949)
Source URL:
First approved in 1949
Source:
Panparnit HCl by Geigy
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Caramiphen is a muscarinic M1 acetylcholine receptor antagonist, which was used for the treatment of Parkinson Disease and cough, but then there using were discontinued. Caramiphen is also used in local anesthesia, and effect could be achieved through the suppression of voltage-gated Na⁺ currents.
Status:
US Previously Marketed
Source:
Thiantoin Sodium by Lilly
(1949)
Source URL:
First approved in 1949
Source:
Thiantoin Sodium by Lilly
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Conditions:

THIANTOIN (also known as phethenylate) is an anticonvulsant drug.
Status:
US Previously Marketed
First approved in 1949

Class (Stereo):
CHEMICAL (ABSOLUTE)



Metocurine, also known as dimethyltubocurarine, is a non-depolarizing muscle relaxant through the neuromuscular blockade. It antagonizes the neurotransmitter action of acetylcholine by binding competitively with cholinergic receptor sites on the motor end-plate. Patients chronically receiving anticonvulsants are relatively resistant to metocurine.

Showing 158451 - 158460 of 167129 results