Iodine-labeled ioglycamic acid (Bilivistan or Biligram) has been used as a contrast medium for intravenous cholangiocystography.

Ioxitalamic acid is a contrast media, which was used as a meglumine salt under the name Telebrix for intravenous urography; computed tomography; digital angiography; angiocardiography (ventriculography, coronary angiography). The drug is no longer available on the market.

Perfluorobutane (PFB) is an inert, high-density colorless gas used as a replacement for Halon 1301 in fire extinguishers, as well as the gas component for newer generation microbubble ultrasound contrast agents. Perflubutane has been used in clinical trials for the diagnostic of Liver Mass, Liver Diseases, Liver Metastasis, Portal Hypertension, and Peripheral Artery Disease. Perflubutane perfusion echocardiography has the potential to be a cost-effective and convenient alternative to nuclear perfusion imaging. Ultrasound enhanced with Perflubutane was able to image myocardial perfusion and obtain information that appears comparable to nuclear imaging.

Ioglicinate, contrast agent, is used in computed tomography.

YTTRIUM Y-90 (YTRACIS®, YTTRIGA®) is a radioactive form of the chemical element yttrium. It is used for radiolabelling other medicines. An example of its use is the treatment of some type of tumors, where the radiolabelled medicine carries the radioactivity to the site of a tumor to destroy the tumor cells.

Fluorocholine-F18 is a tracer for positron emission tomography that can be used in oncology for the evaluation of metastatic prostate cancer, hepatocellular carcinoma, and recurrent brain tumor. After crossing the cell membrane by a carrier-mediated mechanism, Fluorocholine-F18 is converted to cytidinediphosphatecholine and incorporated into phosphatidylcholine which is a component of the cell membrane. This process has been found to be upregulated in malignant cells, providing a mechanism for the enhanced accumulation of radiolabelled choline by neoplasms.

Tauroselcholic acid Se-75 (SeHCAT) is an analog of naturally occurring bile acid conjugate taurocholic acid. It contains a radioactive isotope of selenium, which decays with a half-life of 120 days by emitting gamma-radiation. Tauroselcholic acid is used in clinical tests to diagnose bile acid malabsorption. This is achieved by determining either the excretion of activity in feces or the retention of the activity in the body over a period of days. Tauroselcholic acid is useful in the assessment of ileal involvement in, Crohn's disease, in assessing reduction of ileal absorptive function following certain surgical interventions and in assisting in the classification of patients suffering from chronic diarrhea.

Iobitridol is a contrast medium used for intravenous urography, cerebral computed tomography, computed tomography of the whole body, digital subtraction angiography, arteriography, angiocardiography, venography, CT scan of the thorax. The drug is marketed under the name Xenetix.