Details
Stereochemistry | ACHIRAL |
Molecular Formula | C4F10 |
Molecular Weight | 238.0268 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
FC(F)(F)C(F)(F)C(F)(F)C(F)(F)F
InChI
InChIKey=KAVGMUDTWQVPDF-UHFFFAOYSA-N
InChI=1S/C4F10/c5-1(6,3(9,10)11)2(7,8)4(12,13)14
Perfluorobutane (PFB) is an inert, high-density colorless gas used as a replacement for Halon 1301 in fire extinguishers, as well as the gas component for newer generation microbubble ultrasound contrast agents. Perflubutane has been used in clinical trials for the diagnostic of Liver Mass, Liver Diseases, Liver Metastasis, Portal Hypertension, and Peripheral Artery Disease. Perflubutane perfusion echocardiography has the potential to be a cost-effective and convenient alternative to nuclear perfusion imaging. Ultrasound enhanced with Perflubutane was able to image myocardial perfusion and obtain information that appears comparable to nuclear imaging.
Approval Year
PubMed
Title | Date | PubMed |
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Gateways to clinical trials. | 2006 Dec |
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Removal of perfluorinated surfactants by sorption onto granular activated carbon, zeolite and sludge. | 2008 Aug |
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Developmental neurotoxicity of perfluorinated chemicals modeled in vitro. | 2008 Jun |
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Focal liver tumors: characterization with 3D perflubutane microbubble contrast agent-enhanced US versus 3D contrast-enhanced multidetector CT. | 2009 Apr |
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Definition of contrast enhancement phases of the liver using a perfluoro-based microbubble agent, perflubutane microbubbles. | 2009 Nov |
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Perfluorinated compounds in sediments from the Daliao River system of northeast China. | 2009 Oct |
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Preserving enhancement in freeze-dried contrast agent ST68: Examination of excipients. | 2010 Aug 30 |
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Cooperative infrared to visible up conversion in Tb3+, Eu3+, And Yb3+ containing polymers. | 2010 Dec 14 |
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Perfluorinated compounds in urban river sediments from Guangzhou and Shanghai of China. | 2010 Jun |
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Distribution and sources of polyfluoroalkyl substances (PFAS) in the River Rhine watershed. | 2010 Oct |
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Spatial distribution and sources of perfluorochemicals in the NW Mediterranean coastal waters (Catalonia, Spain). | 2010 Sep |
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Ecotoxicological assessment of surfactants in the aquatic environment: combined toxicity of docusate sodium with chlorinated pollutants. | 2010 Sep |
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Microfluidic assembly of monodisperse, nanoparticle-incorporated perfluorocarbon microbubbles for medical imaging and therapy. | 2010 Sep 7 |
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WHO-ATC |
V08DA06
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NCI_THESAURUS |
C390
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355-25-9
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C069727
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PERFLUOROBUTANE
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C76636
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DB12821
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CHEMBL2104979
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C108042
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3999
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ACTIVE MOIETY