IOBITRIDOL

Details

Stereochemistry	MIXED
Molecular Formula	C20H28I3N3O9
Molecular Weight	835.1644
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN(CC(O)CO)C(=O)C1=C(I)C(C(=O)N(C)CC(O)CO)=C(I)C(NC(=O)C(CO)CO)=C1I

InChI

InChIKey=YLPBXIKWXNRACS-UHFFFAOYSA-N

InChI=1S/C20H28I3N3O9/c1-25(3-10(31)7-29)19(34)12-14(21)13(20(35)26(2)4-11(32)8-30)16(23)17(15(12)22)24-18(33)9(5-27)6-28/h9-11,27-32H,3-8H2,1-2H3,(H,24,33)

HIDE SMILES / InChI

Molecular Formula	C20H28I3N3O9
Molecular Weight	835.1644
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.aemps.gob.es/cima/pdfs/es/ft/61384/61384_ft.pdf

Iobitridol is a contrast medium used for intravenous urography, cerebral computed tomography, computed tomography of the whole body, digital subtraction angiography, arteriography, angiocardiography, venography, CT scan of the thorax. The drug is marketed under the name Xenetix.

CNS Activity

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Contrast agent 13 Sources: https://www.aemps.gob.es/cima/pdfs/es/ft/61384/61384_ft.pdf	Diagnostic		Approved 8429	XENETIX Approved Use Intravenous urography, cerebral computed tomography, computed tomography of the whole body, digital subtraction angiography, arteriography, angiocardiography, venography, CT scan of the thorax. Launch Date 1993

PubMed

Title	Date	PubMed
Nephrotoxicity of low-osmolality versus iso-osmolality contrast agents: impact of N-acetylcysteine.	2005 Nov	16221226
Nephrotoxicity of low-osmolar and iso-osmolar contrast media.	2006 Mar	16528264

Patents

Sample Use Guides

In Vivo Use Guide

1 ml/kg of Xenetix350 given as intravenous infusion (Intravenous urography, cerebral CT scan), 1,8 ml/kg (CT scan of the whole body), 2,2-3,6 ml/kg (arteriography), 1,9-4,6 ml/kg (angiocardiography).

Route of Administration: Other

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:40:22 GMT 2023` Edited by `admin` on `Fri Dec 15 15:40:22 GMT 2023`
Record UNII	182ECH14UH
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

IOBITRIDOL

Official Name

English

1,3-BENZENEDICARBOXAMIDE, N1,N3-BIS(2,3-DIHYDROXYPROPYL)-5-((3-HYDROXY-2-(HYDROXYMETHYL)-1-OXOPROPYL)AMINO)-2,4,6-TRIIODO-N1,N3-DIMETHYL-

Systematic Name

English

N,N'-BIS(2,3-DIHYDROXYPROPYL)-5-(2-(HYDROXYMETHYL)HYDRACRYLAMIDO)-2,4,6-TRIIODO-N,N'-DIMETHYLISOPHTHALAMIDE

Systematic Name

English

IOBITRIDOL [JAN]

Common Name

English

iobitridol [INN]

Common Name

English

N,N'-BIS(2,3-DIHYDROXYPROPYL)-5-((3-HYDROXY-2-(HYDROXYMETHYL)-1-OXOPROPYL)AMINO)-2,4,6-TRIIODO-N,N'-DIMETHYL-1,3-BENZENEDICARBOXAMIDE

Systematic Name

English

IOBITRIDOL [MI]

Common Name

English

IOBITRIDOL [MART.]

Common Name

English

5-(3-HYDROXY-2-(HYDROXYMETHYL)-PROPIONAMIDO)-N,N'-DIMETHYL-N,N'-BIS-(2,3-DIHYDROXYPROPYL)-2,4,6-TRIIODOISOPHTHALAMIDE

Systematic Name

English

Iobitridol [WHO-DD]

Common Name

English

Classification Tree Code System Code

WHO-ATC

V08AB11