U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C4F10
Molecular Weight 238.0268
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PERFLUBUTANE

SMILES

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)F

InChI

InChIKey=KAVGMUDTWQVPDF-UHFFFAOYSA-N
InChI=1S/C4F10/c5-1(6,3(9,10)11)2(7,8)4(12,13)14

HIDE SMILES / InChI

Molecular Formula C4F10
Molecular Weight 238.0268
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Perfluorobutane (PFB) is an inert, high-density colorless gas used as a replacement for Halon 1301 in fire extinguishers, as well as the gas component for newer generation microbubble ultrasound contrast agents. Perflubutane has been used in clinical trials for the diagnostic of Liver Mass, Liver Diseases, Liver Metastasis, Portal Hypertension, and Peripheral Artery Disease. Perflubutane perfusion echocardiography has the potential to be a cost-effective and convenient alternative to nuclear perfusion imaging. Ultrasound enhanced with Perflubutane was able to image myocardial perfusion and obtain information that appears comparable to nuclear imaging.

Approval Year

PubMed

Substance Class Chemical
Record UNII
SE4TWR0K2C
Record Status Validated (UNII)
Record Version