U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 8571 - 8580 of 141793 results

Status:
Investigational
Source:
INN:cyprenorphine
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Cyprenorphine is a mixed agonist-antagonist of opioid receptors. In clinical trials, administration of cyprenorphine induced psychotomimetic effects in pre-operative patients.
Status:
Investigational
Source:
INN:nihydrazone
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Nihydrazone, a feed additive for chickens, has both antibacterial and antiprotozoal activity. It was found to be effective against coccidiosis due to Eimeria tenella and E. necatrix and it prevented an outbreak of cecal coccidiosis, reduced the incidence of "air sac infection," improved weight gains, feed conversions and livability and, in addition, it was active against fowl typhoid.
Cycloheximide is an antibiotic produced by fermentation culture of Streptomyces griseus, Streptomyces noursei, Streptomyces albulus, Streptomyces naraensis, or other cycloheximide-producing microorganism. It was first discovered by A. Whiffen et al. in 1946. She observed the activity of the compound against the yeasts and it became known as the first antifungal antibiotic. Cycloheximide has been marketed as a plant fungicide for many years and this use continues mainly against fungal diseases of turf and for powdery mildew on roses. More recently, cycloheximide has been recognized and is being developed as an abscission agent for citrus fruits and olives. Due to significant toxic side effects, including DNA damage, teratogenesis, and other reproductive effects, cycloheximide is generally used only in in vitro research applications, and is not suitable for human use as a therapeutic compound. Cycloheximide is an antimitotic and an inhibitor of the synthesis of both DNA and protein.
Status:
Investigational
Source:
INN:picolamine [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Picolylamine (PA), a derivatizing agent displaying a highly ESI-active pyridyl group that reacts with carboxylic acids in the presence of a condensation agent to form an amide derivative. Picolylamine is used as a derivatization reagent for the detection of endogenous carboxylic acids.
Status:
Investigational
Source:
INN:sulfabenz
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Sulfabenz is an antibacterial; coccidiostat (for poultry).
Status:
Investigational
Source:
NCT00854737: Phase 2 Interventional Completed Bipolar Disorder
(2004)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



Cytidine is a substrate of the uridine-cytidine kinase and is a part nucleic acids. It can serve as a substrate for the salvage pathway of pyrimidine nucleotide synthesis, as a precursor of the cytidine triphosphate (CTP) needed in the phosphatidylcholine (PC) and phosphatidylethanolamine (PE) biosynthetic pathway. Cytidine was also used under the brand name posilent in Germany for the treatment of muscular, accommodative, and nervous eye disorders.
Status:
Investigational
Source:
INN:leniquinsin
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Leniquinsin acts as a vasodilator and shows antihypertensive effects. It is a potent rat brain phosphodiesterase inhibitor. Its hypotensive effect would seem to be due to alpha-adrenergic blockade and to a direct action on smooth muscle.
Status:
Investigational
Source:
USAN:CLOTICASONE PROPIONATE [USAN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Cloticasone propionate is an ester of an antiinflammation steroid cloticasone.
Status:
Investigational
Source:
INN:enpromate [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Enpromate is an antineoplastic agent.
Status:
Investigational
Source:
USAN:LIOTHYRONINE I 125 [USAN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

A radioconjugate of synthetic active thyroid hormone, liothyronine (T3), labeled with Iodine 125. Liothyronine involves many important metabolic functions and is essential to the proper development and differentiation of all cells. I-125 liothyronine may be used in radiotherapy in thyroid cancers. It was used for the thyroxine T4 determination in serum by competitive protein-binding analysis.

Showing 8571 - 8580 of 141793 results