NIHYDRAZONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H7N3O4
Molecular Weight	197.1482
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(=O)N\N=C\C1=CC=C(O1)[N+]([O-])=O

InChI

InChIKey=ACFHHZJOAUZSJU-XBXARRHUSA-N

InChI=1S/C7H7N3O4/c1-5(11)9-8-4-6-2-3-7(14-6)10(12)13/h2-4H,1H3,(H,9,11)/b8-4+

HIDE SMILES / InChI

Molecular Formula	C7H7N3O4
Molecular Weight	197.1482
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/17649352

Nihydrazone, a feed additive for chickens, has both antibacterial and antiprotozoal activity. It was found to be effective against coccidiosis due to Eimeria tenella and E. necatrix and it prevented an outbreak of cecal coccidiosis, reduced the incidence of "air sac infection," improved weight gains, feed conversions and livability and, in addition, it was active against fowl typhoid.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Coccidiosis due to Eimeria tenella and E. necatrix 1 Sources: https://www.ncbi.nlm.nih.gov/pubmed/17649352	Preventing		Not Provided 504	Unknown Approved Use Unknown
Fowl typhoid 4 Sources: https://www.ncbi.nlm.nih.gov/pubmed/17649352	Preventing		Not Provided 504	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
THE ACTIVITY OF NIHYDRAZONE IN EIMERIA TENELLA INFECTIONS--LABORATORY TRAILS.	1965 Feb	14253992
THE EFFECT OF NIDROXYZONE AND NIHYDRAZONE ON LAYING HENS.	1965 Mar	14340744
COMPARATIVE ACTIVITY OF NIHYDRAZONE AND FURAZOLIDONE AGAINST SALMONELLA GALLINARUM AND ESCHERICHIA COLI IN CHICKENS.	1965 Mar	14340751
THE ANTICOCCIDIAL ACTIVITY OF NIHYDRAZONE.	1965 Mar	14340754
Effect of chemotherapeutic agents on Pasteurella anatipestifer infection in White Pekin ducklings.	1980 May	7393839

Patents

Sample Use Guides

In Vivo Use Guide

feed for chicken

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:06:26 GMT 2023` Edited by `admin` on `Fri Dec 15 15:06:26 GMT 2023`
Record UNII	8BS3E41XVP
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NIHYDRAZONE

Official Name

English

nihydrazone [INN]

Common Name

English

ACETIC ACID 5-NITROFURFURYLIDENEHYDRAZIDE

Common Name

English

NSC-6463

Code

English

NIHYDRAZONE [MI]

Common Name

English

Code System Code Type Description

CAS

67-28-7