LENIQUINSIN

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H20N2O4
Molecular Weight	352.3838
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

SMILES

COC1=CC=C(C=NC2=CC=NC3=C2C=C(OC)C(OC)=C3)C=C1OC

InChI

InChIKey=JIGAQXOHSFIRIS-UUYOSTAYSA-N

InChI=1S/C20H20N2O4/c1-23-17-6-5-13(9-18(17)24-2)12-22-15-7-8-21-16-11-20(26-4)19(25-3)10-14(15)16/h5-12H,1-4H3/b22-12-

HIDE SMILES / InChI

Description

Leniquinsin acts as a vasodilator and shows antihypertensive effects. It is a potent rat brain phosphodiesterase inhibitor. Its hypotensive effect would seem to be due to alpha-adrenergic blockade and to a direct action on smooth muscle.

Approval Year

PubMed

PubMed

Show entries

Title	Date	PubMed
Synthesis and hypotensive properties of new 4-aminoquinolines.	1971 Nov	5115204
Heterogeneity of biochemical actions among vasodilators.	1982 Jan	6276530

Showing 1 to 2 of 2 entries

Previous1Next

Show entries

Name

Type

Language

LENIQUINSIN

Official Name

English

EU-1085

Code

English

leniquinsin [INN]

Common Name

English

6,7-Dimethoxy-4-(veratrylideneamino)quinoline

Systematic Name

English

LENIQUINSIN [USAN]

Common Name

English

Showing 1 to 5 of 7 entries

Previous1 2Next

Show entries

Code System

Code

Type

Description

FDA UNII

G53DC63OCM

PRIMARY

CAS

10351-50-5

PRIMARY

ChEMBL

CHEMBL2106354

PRIMARY

SMS_ID

100000082570

PRIMARY

NSC

201115

PRIMARY

Showing 1 to 5 of 10 entries

Previous1 2Next

ACTIVE MOIETY


					G53DC63OCM

LENIQUINSIN