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Details

Stereochemistry ACHIRAL
Molecular Formula C20H20N2O4
Molecular Weight 352.3838
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of LENIQUINSIN

SMILES

COC1=CC=C(C=NC2=CC=NC3=CC(OC)=C(OC)C=C23)C=C1OC

InChI

InChIKey=JIGAQXOHSFIRIS-UUYOSTAYSA-N
InChI=1S/C20H20N2O4/c1-23-17-6-5-13(9-18(17)24-2)12-22-15-7-8-21-16-11-20(26-4)19(25-3)10-14(15)16/h5-12H,1-4H3/b22-12-

HIDE SMILES / InChI

Molecular Formula C20H20N2O4
Molecular Weight 352.3838
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Description

Leniquinsin acts as a vasodilator and shows antihypertensive effects. It is a potent rat brain phosphodiesterase inhibitor. Its hypotensive effect would seem to be due to alpha-adrenergic blockade and to a direct action on smooth muscle.

Approval Year

PubMed

Substance Class Chemical
Record UNII
G53DC63OCM
Record Status Validated (UNII)
Record Version