CYPRENORPHINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C26H33NO4
Molecular Weight	423.5445
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CYPRENORPHINE

Structure Search

SMILES

CO[C@]12C=C[C@@]3(C[C@@H]1C(C)(C)O)[C@H]4CC5=CC=C(O)C6=C5[C@@]3(CCN4CC7CC7)[C@H]2O6

InChI

InChIKey=VSKIOMHXEUHYSI-KNLIIKEYSA-N

InChI=1S/C26H33NO4/c1-23(2,29)18-13-24-8-9-26(18,30-3)22-25(24)10-11-27(14-15-4-5-15)19(24)12-16-6-7-17(28)21(31-22)20(16)25/h6-9,15,18-19,22,28-29H,4-5,10-14H2,1-3H3/t18-,19-,22-,24-,25+,26-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C26H33NO4
Molecular Weight	423.5445
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5647307 | https://www.ncbi.nlm.nih.gov/pubmed/5390897

Cyprenorphine is a mixed agonist-antagonist of opioid receptors. In clinical trials, administration of cyprenorphine induced psychotomimetic effects in pre-operative patients.

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:06:28 GMT 2023` Edited by `admin` on `Fri Dec 15 15:06:28 GMT 2023`
Record UNII	1P6HEG5ZHS
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CYPRENORPHINE

Official Name

English

6,7,8,14-N-(CYCLOPROPYLMETHYL)TETRAHYDRO-7.ALPHA.-(1-HYDROXY-1-METHYLETHYL)-6,14-ENDO-ETHENONORORIPAVINE

Common Name

English

cyprenorphine [INN]

Common Name

English

CYPRENORPHINE [MI]

Common Name

English

Classification Tree Code System Code

DEA NO.

9054

Created by admin on Fri Dec 15 15:06:28 GMT 2023 , Edited by admin on Fri Dec 15 15:06:28 GMT 2023

NCI_THESAURUS

C67413

Created by admin on Fri Dec 15 15:06:28 GMT 2023 , Edited by admin on Fri Dec 15 15:06:28 GMT 2023

Code System Code Type Description

ChEMBL

CHEMBL2110789

Created by admin on Fri Dec 15 15:06:28 GMT 2023 , Edited by admin on Fri Dec 15 15:06:28 GMT 2023

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MESH

C004641

Created by admin on Fri Dec 15 15:06:28 GMT 2023 , Edited by admin on Fri Dec 15 15:06:28 GMT 2023

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EVMPD

SUB06873MIG

Created by admin on Fri Dec 15 15:06:28 GMT 2023 , Edited by admin on Fri Dec 15 15:06:28 GMT 2023

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SMS_ID

100000083781

Created by admin on Fri Dec 15 15:06:28 GMT 2023 , Edited by admin on Fri Dec 15 15:06:28 GMT 2023

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FDA UNII

1P6HEG5ZHS

Created by admin on Fri Dec 15 15:06:28 GMT 2023 , Edited by admin on Fri Dec 15 15:06:28 GMT 2023

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WIKIPEDIA

CYPRENORPHINE

Created by admin on Fri Dec 15 15:06:28 GMT 2023 , Edited by admin on Fri Dec 15 15:06:28 GMT 2023

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MERCK INDEX

m4036

Created by admin on Fri Dec 15 15:06:28 GMT 2023 , Edited by admin on Fri Dec 15 15:06:28 GMT 2023

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Merck Index

INN

2287

Created by admin on Fri Dec 15 15:06:28 GMT 2023 , Edited by admin on Fri Dec 15 15:06:28 GMT 2023

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NCI_THESAURUS

C87355

Created by admin on Fri Dec 15 15:06:28 GMT 2023 , Edited by admin on Fri Dec 15 15:06:28 GMT 2023

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DRUG BANK

DB01480

Created by admin on Fri Dec 15 15:06:28 GMT 2023 , Edited by admin on Fri Dec 15 15:06:28 GMT 2023

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CAS

4406-22-8

Created by admin on Fri Dec 15 15:06:28 GMT 2023 , Edited by admin on Fri Dec 15 15:06:28 GMT 2023

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PUBCHEM

20054882

Created by admin on Fri Dec 15 15:06:28 GMT 2023 , Edited by admin on Fri Dec 15 15:06:28 GMT 2023

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EPA CompTox

DTXSID80905125

Created by admin on Fri Dec 15 15:06:28 GMT 2023 , Edited by admin on Fri Dec 15 15:06:28 GMT 2023

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Related Record Type Details


					1P6HEG5ZHS

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