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Details

Stereochemistry ACHIRAL
Molecular Formula C6H8N2.2ClH
Molecular Weight 181.063
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 3-AMINOMETHYLPYRIDINE DIHYDROCHLORIDE

SMILES

Cl.Cl.NCC1=CN=CC=C1

InChI

InChIKey=RBXRFBJTZFYBSZ-UHFFFAOYSA-N
InChI=1S/C6H8N2.2ClH/c7-4-6-2-1-3-8-5-6;;/h1-3,5H,4,7H2;2*1H

HIDE SMILES / InChI
Molecular Formula C6H8N2
Molecular Weight 108.1411
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: The description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/28391832

Picolylamine (PA), a derivatizing agent displaying a highly ESI-active pyridyl group that reacts with carboxylic acids in the presence of a condensation agent to form an amide derivative. Picolylamine is used as a derivatization reagent for the detection of endogenous carboxylic acids.

Originator

Seide, O.
2
Sources: Berichte der Deutschen Chemischen Gesellschaft [Abteilung] B: Abhandlungen (1924), 57B, 1802-6

Approval Year

Unknown
149124
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Isolation and characterization of low-sulphur-tolerant mutants of Arabidopsis.
2010-07
(3-Pyrid-yl)methanaminium 4-nitro-phenolate 4-nitro-phenol solvate.
2010-06-16
The prognostic IDH1( R132 ) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma.
2010-04
Bis(3-ammonio-methyl-pyridinium) cyclo-tetra-phosphate.
2010-03-10
6-Allyl-3-(6-chloro-3-pyridylmeth-yl)-6,7-dihydro-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-imine.
2009-11-25
Redetermination of 3-(ammonio-meth-yl)pyridinium dichloride.
2009-07-11
Spectrometric study of tautomeric and protonation equilibria of o-vanillin Schiff base derivatives and their complexes with Cu(II).
2008-12-15
Ligand oxidation of a deprotonated bis(picolyl)amine Ir(I)(cod) complex.
2008
Variations in product in reactions of naphthoquinone with primary amines.
2007-03-01
Silver(I) 3-aminomethylpyridine complexes, part 2: effect of ligand ratio, hydrogen bonding, and pi-stacking with an interacting anion.
2006-03-20
Silver(I) 3-aminomethylpyridine complexes, part 1: effect of ligand ratio, pi-stacking, and temperature with a noninteracting anion.
2006-03-20
[Raman spectroscopic study of human serum albumin interacting with 3-picolylamine].
2006-03
A general procedure for the enantioselective synthesis of the minor tobacco alkaloids nornicotine, anabasine, and anatabine.
2005-10-31
(99m)Tc human IgG radiolabelled by HYNIC. Biodistribution and scintigraphy of experimentally induced inflammatory lesions in animal model.
2004
New N-pyridinyl(methyl)-indole-2- and 3-(alkyl)carboxamides and derivatives acting as systemic and topical inflammation inhibitors.
2002-12
Biological evaluation of hepatitis C virus helicase inhibitors.
2001-07-09
Patents

Patents

03994905
8
04268676
7
04374248
5
04380638
5
04659725
9
04820822
21
05252741
3
05395838
2
05554783
3
05633375
2
05698579
2
05843942
3
05922711
7
20040116460
2
7101891
2
JP4791375B2
8
JPS5896087A
3

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:46:35 GMT 2025
Edited
by admin
on Mon Mar 31 17:46:35 GMT 2025
Record UNII
0HGC7ZD530
Record Status Validated (UNII)
Record Version
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Name Type Language
3-AMINOMETHYLPYRIDINE DIHYDROCHLORIDE
Preferred Name English
Code System Code Type Description
PUBCHEM
31017
Created by admin on Mon Mar 31 17:46:35 GMT 2025 , Edited by admin on Mon Mar 31 17:46:35 GMT 2025
PRIMARY
CAS
22199-21-9
Created by admin on Mon Mar 31 17:46:35 GMT 2025 , Edited by admin on Mon Mar 31 17:46:35 GMT 2025
PRIMARY
FDA UNII
0HGC7ZD530
Created by admin on Mon Mar 31 17:46:35 GMT 2025 , Edited by admin on Mon Mar 31 17:46:35 GMT 2025
PRIMARY
EPA CompTox
DTXSID00176734
Created by admin on Mon Mar 31 17:46:35 GMT 2025 , Edited by admin on Mon Mar 31 17:46:35 GMT 2025
PRIMARY
Related Record Type Details
Structure of Picolamine
PARENT -> SALT/SOLVATE
NIH
NCATS
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