Picolamine

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H8N2
Molecular Weight	108.1411
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NCC1=CN=CC=C1

InChI

InChIKey=HDOUGSFASVGDCS-UHFFFAOYSA-N

InChI=1S/C6H8N2/c7-4-6-2-1-3-8-5-6/h1-3,5H,4,7H2

HIDE SMILES / InChI

Molecular Formula	C6H8N2
Molecular Weight	108.1411
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/24041657
Curator's Comment: The description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/28391832

Picolylamine (PA), a derivatizing agent displaying a highly ESI-active pyridyl group that reacts with carboxylic acids in the presence of a condensation agent to form an amide derivative. Picolylamine is used as a derivatization reagent for the detection of endogenous carboxylic acids.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

PubMed

Title	Date	PubMed
Isolation and characterization of low-sulphur-tolerant mutants of Arabidopsis.	2010-07	20547563
(3-Pyrid-yl)methanaminium 4-nitro-phenolate 4-nitro-phenol solvate.	2010-06-16	21587877
The prognostic IDH1( R132 ) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma.	2010-04	20127344
Bis(3-ammonio-methyl-pyridinium) cyclo-tetra-phosphate.	2010-03-10	21580621
6-Allyl-3-(6-chloro-3-pyridylmeth-yl)-6,7-dihydro-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-imine.	2009-11-25	21578906
Redetermination of 3-(ammonio-meth-yl)pyridinium dichloride.	2009-07-11	21583517
Spectrometric study of tautomeric and protonation equilibria of o-vanillin Schiff base derivatives and their complexes with Cu(II).	2008-12-15	18456546
Ligand oxidation of a deprotonated bis(picolyl)amine Ir(I)(cod) complex.	2008	19016555
Variations in product in reactions of naphthoquinone with primary amines.	2007-03-01	17331232
Silver(I) 3-aminomethylpyridine complexes, part 2: effect of ligand ratio, hydrogen bonding, and pi-stacking with an interacting anion.	2006-03-20	16529486
Silver(I) 3-aminomethylpyridine complexes, part 1: effect of ligand ratio, pi-stacking, and temperature with a noninteracting anion.	2006-03-20	16529485
[Raman spectroscopic study of human serum albumin interacting with 3-picolylamine].	2006-03	16830755
A general procedure for the enantioselective synthesis of the minor tobacco alkaloids nornicotine, anabasine, and anatabine.	2005-10-31	16353951
(99m)Tc human IgG radiolabelled by HYNIC. Biodistribution and scintigraphy of experimentally induced inflammatory lesions in animal model.	2004	15968595
New N-pyridinyl(methyl)-indole-2- and 3-(alkyl)carboxamides and derivatives acting as systemic and topical inflammation inhibitors.	2002-12	12683678
Biological evaluation of hepatitis C virus helicase inhibitors.	2001-07-09	11425528

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Wed Apr 02 08:28:42 GMT 2025` Edited by `admin` on `Wed Apr 02 08:28:42 GMT 2025`
Record UNII	31LA41942J
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NSC-59706

Preferred Name

English

Picolamine

Official Name

English

Pyridine, 3-(aminomethyl)-

Systematic Name

English

3-Pyridinemethanamine

Systematic Name

English

Picolamine [WHO-DD]

Common Name

English

3-Aminomethylpyridine

Systematic Name

English

picolamine [INN]

Common Name

English

Code System Code Type Description

CAS

3731-52-0