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5

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3

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Primary Target

Histamine H1 receptor

1

Neutrophil cytosol factor 1

1

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Phase I

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Asthma

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Ischemic stroke

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Originator

Seide, O.

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Schmiedeberg, O.

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Showing 1 - 8 of 8 results

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APOCYNIN

B6J7B9UDTR

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Status:

Investigational

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Neutrophil cytosol factor 1

Conditions:

Ischemic stroke

Rheumatoid arthritis

Chronic obstructive pulmonary disease

Parkinson's disease

Apocynin, also known as acetovanillone, is a natural organic compound related to vanillin. It has been isolated from a variety of plant sources. Metabolites of apocynin are able to block the activity of NADPH oxidase, thus giving apocynin antioxidant...

and anti-inflammatory capabilities. Effects of apocynin on the concentration of reactive oxygen and nitrogen species in patients with asthma and chronic obstructive pulmonary disease were investigated in phase I clinical trials. In preclinical models, it was found that apocynin provides neuroprotective effects in models of stroke and Parkinson's disease.

3-AMINOMETHYLPYRIDINE DIHYDROCHLORIDE

0HGC7ZD530

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Status:

Investigational

Class (Stereo):

CHEMICAL (ACHIRAL)

Conditions:

Picolylamine (PA), a derivatizing agent displaying a highly ESI-active pyridyl group that reacts with carboxylic acids in the presence of a condensation agent to form an amide derivative. Picolylamine is used as a derivatization reagent for the detec...

tion of endogenous carboxylic acids.

2-PYRIDINEETHANAMINE

ATW1AH7OJ5

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Histamine H1 receptor

3-CARBOXYBENZALDEHYDE

HB95GRM95D

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

N,N-BIS(3-AMINOPROPYL)METHYLAMINE

62ZM34D74O

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

SALICYLALDEHYDE

17K64GZH20

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

Picolamine

31LA41942J

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Status:

Investigational

Class (Stereo):

CHEMICAL (ACHIRAL)

Conditions:

Picolylamine (PA), a derivatizing agent displaying a highly ESI-active pyridyl group that reacts with carboxylic acids in the presence of a condensation agent to form an amide derivative. Picolylamine is used as a derivatization reagent for the detec...

tion of endogenous carboxylic acids.

Sodium salicylaldehyde

79T8FTQ9F3

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

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