U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C7H10N2
Molecular Weight 122.1677
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2-PYRIDINEETHANAMINE

SMILES

NCCC1=CC=CC=N1

InChI

InChIKey=XPQIPUZPSLAZDV-UHFFFAOYSA-N
InChI=1S/C7H10N2/c8-5-4-7-3-1-2-6-9-7/h1-3,6H,4-5,8H2

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
5.9 null [pIC50]
PubMed

PubMed

TitleDatePubMed
Neuropharmacology of vestibular system disorders.
2010-03
One-dimensional spin-crossover Iron(II) complexes bridged by intermolecular imidazole-pyridine NH...N hydrogen bonds, [Fe(HL(Me))(3)]X(2) (HL(Me) = (2-methylimidazol-4-yl-methylideneamino-2-ethylpyridine; X = PF(6), ClO(4), BF(4)).
2010-02-15
Polymer-bound oxidovanadium(IV) and dioxidovanadium(V) complexes: synthesis, characterization and catalytic application for the hydroamination of styrene and vinyl pyridine.
2009-11-21
New photomagnetic cyanido-bridged Cu(II)-Mo(IV) oligonuclear complexes: slight modification of the blocking ligands induces different structures.
2009-10-07
Mast cells down-regulate CD4+CD25+ T regulatory cell suppressor function via histamine H1 receptor interaction.
2009-09-01
2-[2-(2-Pyrid-yl)eth-yl]isoindolinium perchlorate.
2009-08-19
Syntheses, X-ray structures, and physicochemical properties of phenoxo-bridged dinuclear nickel(II) complexes: kinetics of transesterification of 2-hydroxypropyl-p-nitrophenylphosphate.
2009-08-17
Automated potentiometric titrations in KCl/water-saturated octanol: method for quantifying factors influencing ion-pair partitioning.
2009-04-01
2-(2-Ammonio-ethyl)pyridinium hexa-chloridorhenate(IV).
2009-02-04
Histamine excites rat lateral vestibular nuclear neurons through activation of post-synaptic H2 receptors.
2008-12-19
μ-Squarato-κO:O-bis-{[2-(2-amino-ethyl)pyridine-κN,N']aqua-nickel(II)} squarate 0.25-hydrate.
2008-09-27
Formation of {Cu2(III)(mu-O)2}2+ core due to dioxygen reactivity of a copper(I) complex supported by a new hybrid tridentate ligand: reaction with exogenous substrates.
2008-08
Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells.
2008-06-06
Bis{μ-2-[2-(2-pyrid-yl)ethyl-imino-meth-yl]phenolato}bis-[azido-zinc(II)].
2008-05-10
Metal-assisted in situ formation of a tridentate acetylacetone ligand for complexation of fac-Re(CO)3+ for radiopharmaceutical applications.
2008-04-07
Synthesis of 17beta-estradiol-platinum(II) hybrid molecules showing cytotoxic activity on breast cancer cell lines.
2008-04-01
Pro-apoptotic activity of novel Isatin-Schiff base copper(II) complexes depends on oxidative stress induction and organelle-selective damage.
2007-04-20
Ligand effects on Ni(II)-catalysed alkane-hydroxylation with m-CPBA.
2007-03-21
Carbonic anhydrase activators: an activation study of the human mitochondrial isoforms VA and VB with amino acids and amines.
2007-03-01
Dicopper(II) complexes of a new pyrazolate-containing Schiff-base macrocycle and related acyclic ligand.
2007-01-28
Histamine decreases myogenic tone in rat cerebral arteries by H2-receptor-mediated KV channel activation, independent of endothelium and cyclic AMP.
2006-10-10
Excitatory effect of histamine on neuronal activity of rat globus pallidus by activation of H2 receptors in vitro.
2005-11
Isatin-Schiff base copper(II) complexes and their influence on cellular viability.
2005-07
Silver(I) complexes of 2-(2-aminoethyl)pyridine: nitrate and perchlorate salts of bis[mu-2-(2-aminoethyl)pyridine-kappa(2)N:N']disilver(I).
2005-06
Biological evaluation of novel estrogen-platinum(II) hybrid molecules on uterine and ovarian cancers-molecular modeling studies.
2004-12-06
Involvement of hypothalamic histamine H1 receptor in the regulation of feeding rhythm and obesity.
2004-09
Dimetallic complexes of acyclic pyridine-armed ligands derived from 3,6-diformylpyridazine.
2004-07-21
Large-scale overproduction, functional purification and ligand affinities of the His-tagged human histamine H1 receptor.
2004-07
Bis(saccharinato-kappa N)zinc(II) complexes with N,N'-bidentate 2-aminomethylpyridine and 2-aminoethylpyridine.
2004-01
Synthesis of 17beta-estradiol platinum(II) complexes: biological evaluation on breast cancer cell lines.
2003-11-17
Histamine elicits neuronal excitatory response of red nucleus in the rat via H2 receptors in vitro.
2003-11-06
Nickel(II) cyclidenes with appended ethylpyridine receptor centers as molecular tweezers for dicarboxylic acids.
2003-10-20
Histamine-induced chloride secretion is mediated via H2-receptors in the pig proximal colon.
2003-02
Excitatory effects of histamine on cerebellar interpositus nuclear cells of rats through H(2) receptors in vitro.
2002-09-06
Histamine H1 receptors are involved in mouse nasal allergic responses: a demonstration with H1 receptor-deficient mice.
2002-05
Contractile response of horse deep dorsal penile vein to histamine.
2002-04
Oxo-transfer reaction from a bis(mu-oxo)dicopper(III) complex to sulfides.
2002-02-13
Formation, characterization, and reactivity of bis(mu-oxo)dinickel(III) complexes supported by a series of bis[2-(2-pyridyl)ethyl]amine ligands.
2001-11-14
Effects of betahistine and of its metabolites on vestibular sensory organs.
2001-06
H3 receptor-mediated inhibition of intestinal acetylcholine release: pharmacological characterization of signal transduction pathways.
2001-02
Regulation of interleukin-6, and macrophage colony-stimulating factor mRNA levels by histamine in stromal cell line (MC3T3-G2/PA6).
1998-05
Patents
Name Type Language
NSC-71989
Preferred Name English
2-PYRIDINEETHANAMINE
Systematic Name English
2-(2-PYRIDINYL)ETHANAMINE
Systematic Name English
2-(2-AMINOETHYL)PYRIDINE
Systematic Name English
DEMETHYLBETAHISTINE
Common Name English
.ALPHA.-(2-AMINOETHYL)PYRIDINE
Common Name English
2-(2'-AMINOETHYL)PYRIDINE
Common Name English
2-(2-PYRIDYL)ETHYLAMINE
Systematic Name English
.ALPHA.-PYRIDYLETHYLAMINE
Systematic Name English
2'-AMINOETHYL-2-PYRIDINE
Common Name English
N-(2-(2-PYRIDINYL)ETHYL)AMINE
Systematic Name English
PYRIDINE, 2-(2-AMINOETHYL)-
Systematic Name English
Code System Code Type Description
WIKIPEDIA
2-Pyridylethylamine
Created by admin on Mon Mar 31 19:15:09 GMT 2025 , Edited by admin on Mon Mar 31 19:15:09 GMT 2025
PRIMARY
EPA CompTox
DTXSID5022196
Created by admin on Mon Mar 31 19:15:09 GMT 2025 , Edited by admin on Mon Mar 31 19:15:09 GMT 2025
PRIMARY
MESH
C006183
Created by admin on Mon Mar 31 19:15:09 GMT 2025 , Edited by admin on Mon Mar 31 19:15:09 GMT 2025
PRIMARY
ECHA (EC/EINECS)
220-295-1
Created by admin on Mon Mar 31 19:15:09 GMT 2025 , Edited by admin on Mon Mar 31 19:15:09 GMT 2025
PRIMARY
PUBCHEM
75919
Created by admin on Mon Mar 31 19:15:09 GMT 2025 , Edited by admin on Mon Mar 31 19:15:09 GMT 2025
PRIMARY
CHEBI
74024
Created by admin on Mon Mar 31 19:15:09 GMT 2025 , Edited by admin on Mon Mar 31 19:15:09 GMT 2025
PRIMARY
CAS
2706-56-1
Created by admin on Mon Mar 31 19:15:09 GMT 2025 , Edited by admin on Mon Mar 31 19:15:09 GMT 2025
PRIMARY
NSC
71989
Created by admin on Mon Mar 31 19:15:09 GMT 2025 , Edited by admin on Mon Mar 31 19:15:09 GMT 2025
PRIMARY
FDA UNII
ATW1AH7OJ5
Created by admin on Mon Mar 31 19:15:09 GMT 2025 , Edited by admin on Mon Mar 31 19:15:09 GMT 2025
PRIMARY