Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C7H10N2 |
| Molecular Weight | 122.1677 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NCCC1=CC=CC=N1
InChI
InChIKey=XPQIPUZPSLAZDV-UHFFFAOYSA-N
InChI=1S/C7H10N2/c8-5-4-7-3-1-2-6-9-7/h1-3,6H,4-5,8H2
| Molecular Formula | C7H10N2 |
| Molecular Weight | 122.1677 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: CHEMBL231 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14667234 |
5.9 null [pIC50] |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Neuropharmacology of vestibular system disorders. | 2010-03 |
|
| One-dimensional spin-crossover Iron(II) complexes bridged by intermolecular imidazole-pyridine NH...N hydrogen bonds, [Fe(HL(Me))(3)]X(2) (HL(Me) = (2-methylimidazol-4-yl-methylideneamino-2-ethylpyridine; X = PF(6), ClO(4), BF(4)). | 2010-02-15 |
|
| Polymer-bound oxidovanadium(IV) and dioxidovanadium(V) complexes: synthesis, characterization and catalytic application for the hydroamination of styrene and vinyl pyridine. | 2009-11-21 |
|
| New photomagnetic cyanido-bridged Cu(II)-Mo(IV) oligonuclear complexes: slight modification of the blocking ligands induces different structures. | 2009-10-07 |
|
| Mast cells down-regulate CD4+CD25+ T regulatory cell suppressor function via histamine H1 receptor interaction. | 2009-09-01 |
|
| 2-[2-(2-Pyrid-yl)eth-yl]isoindolinium perchlorate. | 2009-08-19 |
|
| Syntheses, X-ray structures, and physicochemical properties of phenoxo-bridged dinuclear nickel(II) complexes: kinetics of transesterification of 2-hydroxypropyl-p-nitrophenylphosphate. | 2009-08-17 |
|
| Automated potentiometric titrations in KCl/water-saturated octanol: method for quantifying factors influencing ion-pair partitioning. | 2009-04-01 |
|
| 2-(2-Ammonio-ethyl)pyridinium hexa-chloridorhenate(IV). | 2009-02-04 |
|
| Histamine excites rat lateral vestibular nuclear neurons through activation of post-synaptic H2 receptors. | 2008-12-19 |
|
| μ-Squarato-κO:O-bis-{[2-(2-amino-ethyl)pyridine-κN,N']aqua-nickel(II)} squarate 0.25-hydrate. | 2008-09-27 |
|
| Formation of {Cu2(III)(mu-O)2}2+ core due to dioxygen reactivity of a copper(I) complex supported by a new hybrid tridentate ligand: reaction with exogenous substrates. | 2008-08 |
|
| Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells. | 2008-06-06 |
|
| Bis{μ-2-[2-(2-pyrid-yl)ethyl-imino-meth-yl]phenolato}bis-[azido-zinc(II)]. | 2008-05-10 |
|
| Metal-assisted in situ formation of a tridentate acetylacetone ligand for complexation of fac-Re(CO)3+ for radiopharmaceutical applications. | 2008-04-07 |
|
| Synthesis of 17beta-estradiol-platinum(II) hybrid molecules showing cytotoxic activity on breast cancer cell lines. | 2008-04-01 |
|
| Pro-apoptotic activity of novel Isatin-Schiff base copper(II) complexes depends on oxidative stress induction and organelle-selective damage. | 2007-04-20 |
|
| Ligand effects on Ni(II)-catalysed alkane-hydroxylation with m-CPBA. | 2007-03-21 |
|
| Carbonic anhydrase activators: an activation study of the human mitochondrial isoforms VA and VB with amino acids and amines. | 2007-03-01 |
|
| Dicopper(II) complexes of a new pyrazolate-containing Schiff-base macrocycle and related acyclic ligand. | 2007-01-28 |
|
| Histamine decreases myogenic tone in rat cerebral arteries by H2-receptor-mediated KV channel activation, independent of endothelium and cyclic AMP. | 2006-10-10 |
|
| Excitatory effect of histamine on neuronal activity of rat globus pallidus by activation of H2 receptors in vitro. | 2005-11 |
|
| Isatin-Schiff base copper(II) complexes and their influence on cellular viability. | 2005-07 |
|
| Silver(I) complexes of 2-(2-aminoethyl)pyridine: nitrate and perchlorate salts of bis[mu-2-(2-aminoethyl)pyridine-kappa(2)N:N']disilver(I). | 2005-06 |
|
| Biological evaluation of novel estrogen-platinum(II) hybrid molecules on uterine and ovarian cancers-molecular modeling studies. | 2004-12-06 |
|
| Involvement of hypothalamic histamine H1 receptor in the regulation of feeding rhythm and obesity. | 2004-09 |
|
| Dimetallic complexes of acyclic pyridine-armed ligands derived from 3,6-diformylpyridazine. | 2004-07-21 |
|
| Large-scale overproduction, functional purification and ligand affinities of the His-tagged human histamine H1 receptor. | 2004-07 |
|
| Bis(saccharinato-kappa N)zinc(II) complexes with N,N'-bidentate 2-aminomethylpyridine and 2-aminoethylpyridine. | 2004-01 |
|
| Synthesis of 17beta-estradiol platinum(II) complexes: biological evaluation on breast cancer cell lines. | 2003-11-17 |
|
| Histamine elicits neuronal excitatory response of red nucleus in the rat via H2 receptors in vitro. | 2003-11-06 |
|
| Nickel(II) cyclidenes with appended ethylpyridine receptor centers as molecular tweezers for dicarboxylic acids. | 2003-10-20 |
|
| Histamine-induced chloride secretion is mediated via H2-receptors in the pig proximal colon. | 2003-02 |
|
| Excitatory effects of histamine on cerebellar interpositus nuclear cells of rats through H(2) receptors in vitro. | 2002-09-06 |
|
| Histamine H1 receptors are involved in mouse nasal allergic responses: a demonstration with H1 receptor-deficient mice. | 2002-05 |
|
| Contractile response of horse deep dorsal penile vein to histamine. | 2002-04 |
|
| Oxo-transfer reaction from a bis(mu-oxo)dicopper(III) complex to sulfides. | 2002-02-13 |
|
| Formation, characterization, and reactivity of bis(mu-oxo)dinickel(III) complexes supported by a series of bis[2-(2-pyridyl)ethyl]amine ligands. | 2001-11-14 |
|
| Effects of betahistine and of its metabolites on vestibular sensory organs. | 2001-06 |
|
| H3 receptor-mediated inhibition of intestinal acetylcholine release: pharmacological characterization of signal transduction pathways. | 2001-02 |
|
| Regulation of interleukin-6, and macrophage colony-stimulating factor mRNA levels by histamine in stromal cell line (MC3T3-G2/PA6). | 1998-05 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:15:09 GMT 2025
by
admin
on
Mon Mar 31 19:15:09 GMT 2025
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| Record UNII |
ATW1AH7OJ5
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| Record Status |
Validated (UNII)
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| Record Version |
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2-Pyridylethylamine
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DTXSID5022196
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C006183
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ATW1AH7OJ5
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