Details
Stereochemistry | ACHIRAL |
Molecular Formula | C7H10N2 |
Molecular Weight | 122.1677 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
NCCC1=CC=CC=N1
InChI
InChIKey=XPQIPUZPSLAZDV-UHFFFAOYSA-N
InChI=1S/C7H10N2/c8-5-4-7-3-1-2-6-9-7/h1-3,6H,4-5,8H2
Molecular Formula | C7H10N2 |
Molecular Weight | 122.1677 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL231 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14667234 |
5.9 null [pIC50] |
PubMed
Title | Date | PubMed |
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Regulation of interleukin-6, and macrophage colony-stimulating factor mRNA levels by histamine in stromal cell line (MC3T3-G2/PA6). | 1998 May |
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Synthesis of 17beta-estradiol platinum(II) complexes: biological evaluation on breast cancer cell lines. | 2003 Nov 17 |
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Histamine elicits neuronal excitatory response of red nucleus in the rat via H2 receptors in vitro. | 2003 Nov 6 |
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Biological evaluation of novel estrogen-platinum(II) hybrid molecules on uterine and ovarian cancers-molecular modeling studies. | 2004 Dec 6 |
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Large-scale overproduction, functional purification and ligand affinities of the His-tagged human histamine H1 receptor. | 2004 Jul |
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Involvement of hypothalamic histamine H1 receptor in the regulation of feeding rhythm and obesity. | 2004 Sep |
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Isatin-Schiff base copper(II) complexes and their influence on cellular viability. | 2005 Jul |
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Excitatory effect of histamine on neuronal activity of rat globus pallidus by activation of H2 receptors in vitro. | 2005 Nov |
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Pro-apoptotic activity of novel Isatin-Schiff base copper(II) complexes depends on oxidative stress induction and organelle-selective damage. | 2007 Apr 20 |
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Synthesis of 17beta-estradiol-platinum(II) hybrid molecules showing cytotoxic activity on breast cancer cell lines. | 2008 Apr 1 |
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Metal-assisted in situ formation of a tridentate acetylacetone ligand for complexation of fac-Re(CO)3+ for radiopharmaceutical applications. | 2008 Apr 7 |
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Histamine excites rat lateral vestibular nuclear neurons through activation of post-synaptic H2 receptors. | 2008 Dec 19 |
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Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells. | 2008 Jun 6 |
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μ-Squarato-κO:O-bis-{[2-(2-amino-ethyl)pyridine-κN,N']aqua-nickel(II)} squarate 0.25-hydrate. | 2008 Sep 27 |
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Automated potentiometric titrations in KCl/water-saturated octanol: method for quantifying factors influencing ion-pair partitioning. | 2009 Apr 1 |
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2-[2-(2-Pyrid-yl)eth-yl]isoindolinium perchlorate. | 2009 Aug 19 |
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2-(2-Ammonio-ethyl)pyridinium hexa-chloridorhenate(IV). | 2009 Feb 4 |
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Polymer-bound oxidovanadium(IV) and dioxidovanadium(V) complexes: synthesis, characterization and catalytic application for the hydroamination of styrene and vinyl pyridine. | 2009 Nov 21 |
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New photomagnetic cyanido-bridged Cu(II)-Mo(IV) oligonuclear complexes: slight modification of the blocking ligands induces different structures. | 2009 Oct 7 |
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Mast cells down-regulate CD4+CD25+ T regulatory cell suppressor function via histamine H1 receptor interaction. | 2009 Sep 1 |
|
Neuropharmacology of vestibular system disorders. | 2010 Mar |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 18:32:52 GMT 2023
by
admin
on
Fri Dec 15 18:32:52 GMT 2023
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Record UNII |
ATW1AH7OJ5
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Record Status |
Validated (UNII)
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Record Version |
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2-Pyridylethylamine
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DTXSID5022196
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C006183
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220-295-1
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75919
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74024
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2706-56-1
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71989
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ATW1AH7OJ5
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