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Class (Stereo):
CHEMICAL (RACEMIC)
Pirepolol is the beta-adrenergic blocking agent. It was developed as an antihypertensive agent.
Class (Stereo):
CHEMICAL (ACHIRAL)
Octimibate is a non-prostanoid inhibitor of platelet aggregation that acts via the prostacyclin receptor.
Class (Stereo):
CHEMICAL (RACEMIC)
Gliamilide is a high-potency sulfamylurea hypoglycemic agent. It has been found to be well tolerated in humans and displays a very short plasma half-life. Like sulfonylureas, gliamilide can lower blood glucose levels by increasing the insulin release from pancreatic beta cells.
Status:
Investigational
Class (Stereo):
CHEMICAL (ABSOLUTE)
Spiclamine (Epsilamine) is a hemostatic agent. It was administered to a total of 23 patients with urological diseases, including 8 postoperative cases. Marked effective, effective and ineffecgive responses were observed in 8, 10 and 5 cases respectively, making 78.3 % of effectiveness. In cases of so-called essential renal bleeding and prostatic disease, a particularly beneticial result was obtained making 93.3 % of marked effectiveness. No serious side effects was seen in all cases treated.
Class (Stereo):
CHEMICAL (ACHIRAL)
Glyprothiazol (VK 57 or RP 2254) is a sulfonamide derivative. This compound lowers blood glucose levels by increasing the release of insulin from the pancreas. It stimulates insulin secretion through a direct action on pancreatic islets. Glyprothiazol was the first of oral hypoglycemic sulfonamides used in the treatment of type 2 diabetes mellitus.
Class (Stereo):
CHEMICAL (ABSOLUTE)
Halocortolone, a synthetic glucocorticoid that was used as a vasoconstrictor, but was never marketed
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Azepexole (or previously known as B-HT 933), a selective alpha 2-adrenoceptor agonist that was studied for the man with physiological tremor. It was shown that the drug produced sedation compared to placebo but not when compared to pre-treatment values. Some studies also have revealed the anti-tussive and antihypertensive properties of azepexole.
Status:
Investigational
Source:
INN:pimetremide [INN]
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Pimetremide is a spasmolytic agent.
Status:
Investigational
Class (Stereo):
CHEMICAL (ABSOLUTE)
Atiratecan (previously known as CH4556300 or TP300), the prodrug of a topoisomerase 1 inhibitor, CH0793076. Atiratecan has been studied in phase II clinical trials to treat cancers (e.g., colorectal cancer; gastric cancer; esophageal cancer), but these studies were suspended.
Class (Stereo):
CHEMICAL (ACHIRAL)
Sulicrinat (also known as HOE 428) is a sulfamoylbenzophenone derivative patented by Hoechst A.-G. as a loop diuretic.