CERICLAMINE

Details

Stereochemistry	RACEMIC
Molecular Formula	C12H17Cl2NO
Molecular Weight	262.175
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN(C)C(C)(CO)CC1=CC=C(Cl)C(Cl)=C1

InChI

InChIKey=FWYRGHMKHZXXQX-UHFFFAOYSA-N

InChI=1S/C12H17Cl2NO/c1-12(8-16,15(2)3)7-9-4-5-10(13)11(14)6-9/h4-6,16H,7-8H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C12H17Cl2NO
Molecular Weight	262.175
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8138956 | https://www.ncbi.nlm.nih.gov/pubmed/7845548 | https://www.ncbi.nlm.nih.gov/pubmed/8915559

Cericlamine (INN) is a potent and moderately selective serotonin reuptake inhibitor (SSRI) of the amphetamine family that was investigated as an antidepressant for the treatment of depression, anxiety disorders, and anorexia nervosa by Jouveinal

Originator

Approval Year

PubMed

Title	Date	PubMed
Central pre- and postsynaptic 5-HT1A receptors in rats treated chronically with a novel antidepressant, cericlamine.	1994 Mar	8138956

Patents

Sample Use Guides

In Vivo Use Guide

Rat: 1, 8, 16 and 32 mg/kg; i.p.

Route of Administration: Intraperitoneal

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:08:38 GMT 2023` Edited by `admin` on `Sat Dec 16 17:08:38 GMT 2023`
Record UNII	VES82D23IB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CERICLAMINE

Official Name

English

cericlamine [INN]

Common Name

English

(±)-3-(3,4-DICHLOROPHENYL)-2-(DIMETHYLAMINO)-2-METHYL-1-PROPANOL

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C47794