CERICLAMINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C12H17Cl2NO
Molecular Weight	262.175
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CERICLAMINE

Structure Search

SMILES

CN(C)C(C)(CO)CC1=CC=C(Cl)C(Cl)=C1

InChI

InChIKey=FWYRGHMKHZXXQX-UHFFFAOYSA-N

InChI=1S/C12H17Cl2NO/c1-12(8-16,15(2)3)7-9-4-5-10(13)11(14)6-9/h4-6,16H,7-8H2,1-3H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8138956 | https://www.ncbi.nlm.nih.gov/pubmed/7845548 | https://www.ncbi.nlm.nih.gov/pubmed/8915559

Cericlamine (INN) is a potent and moderately selective serotonin reuptake inhibitor (SSRI) of the amphetamine family that was investigated as an antidepressant for the treatment of depression, anxiety disorders, and anorexia nervosa by Jouveinal

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
Central pre- and postsynaptic 5-HT1A receptors in rats treated chronically with a novel antidepressant, cericlamine.	1994 Mar	8138956

Patents

Patents

Sample Use Guides

In Vivo Use Guide

Rat: 1, 8, 16 and 32 mg/kg; i.p.

Route of Administration: Intraperitoneal

Name

Type

Language

CERICLAMINE

Official Name

English

cericlamine [INN]

Common Name

English

(±)-3-(3,4-DICHLOROPHENYL)-2-(DIMETHYLAMINO)-2-METHYL-1-PROPANOL

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C47794

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Code System Code Type Description

FDA UNII

VES82D23IB

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PUBCHEM

131074

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MESH

C065524

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INN

6518

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CAS

112922-55-1

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ChEMBL

CHEMBL2106462

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NCI_THESAURUS

C76100

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WIKIPEDIA

Cericlamine

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SMS_ID

100000082065

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EVMPD

SUB07439MIG

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EPA CompTox

DTXSID00869558

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ACTIVE MOIETY


					VES82D23IB