U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 991 - 1000 of 2596 results

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

3-Bromo-1-propanol is an organic compound used in the synthesis of fluorescent halide-sensitive quinolinium dyes and molten salt-polymers. It was used in the synthesis of chiral, quaternary prolines via cyclization of quaternary amino acids. 3-Bromo-1-propanol was used to label surface-accessible tryptophan residues.
Status:
Other

Class (Stereo):
CHEMICAL (RACEMIC)

Conditions:

Glyceryl-1-palmitate (α-Monopalmitin, Glycerol 1-hexadecanoate) is a member of the chemical class known as Monoacylglycerols. Glycerol 1-hexadecanoate is found in fats and oils. Glycerol 1-hexadecanoate is a minor component of olive oil and other vegetable oil. α-Monopalmitin is a glycerol esterified fatty acid, monoacylglycerol, found in lipid structures such as ceramides. 1-Palmitoylglycerol may be used as a substrate for the identification and differentiation of enzymes that hydrolyze or transfer monoacylglycerols such as neuropathy target esterase(s) and monoacylglycerol acyltransferase(s) (MAG).
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

There is no information about pharmacological application of lead nitrate but is known, that this is a toxic substance and probably carcinogenic. Lead substitutes a zinc in the enzyme pyrimidine-5′-nucleotidase, the correct function of this enzyme is very important for the metabolism of DNA.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

There is no information related biological or pharmacological application of sodium diuranate. This is slightly soluble salts, which possesses some toxicity, that has been studied on rabbits
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

2-Bromobiphenyl can be used as reference compound to investigate extraction efficiency of solid-phase microextraction fibers, based on methacrylic acid-trimethylolpropanetrimethacrylate copolymers. It is used in the synthesis of a novel trispirocyclic hydrocarbon having three 9-fluorene moieties around the core of truxene.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

Ethyl glucoside (alpha-anomer) is a component of rice wine and sake and can be found in human urine after exposure to the compound, which is present in these beverages. Ethyl-alpha-D-glucoside was shown to be involved in the maintenance and improvement of skin homeostasis and moisturizing functions. A topical application of ethanol solution of ethyl-alpha-D-glucoside to mice had a positive effect on the epidermis and increased the intercellular lipid content, thus strengthening the barrier function of the epidermis.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

2-aminopurine is a purine analogue. It is known for its mutagenic effect by inducing DNA base-pair transitions. 2-aminopurine is widely used fluorescent probe of DNA structure and the perturbation of that structure by interaction with enzymes and other molecules. 2-aminopurine is a fluorescent nucleobase that provides the means to probe structure and dynamics of RNA molecules. 2-Aminopurine inhibits the double-stranded RNA-dependent protein kinase.
Dimethylphenylpiperazinium (DMPP) is an agonist of nicotinic acetylcholine receptor. DMPP regulates smooth muscle contractility. In addition, it exerts anti-inflammatory properties.
3-Nitropropionic Acid (aka beta-Nitropropionic acid) is a mycotoxin and potent mitochondrial inhibitor. It is produced by a number of fungi and found widely in food, in sugar cane, and in Japanese fungally fermented staples such as miso, soy sauce, and katsuobushi. beta-Nitropropionic acid is also present in some traditional Chinese medicines. beta-Nitropropionic Acid can be systematically administered to produce localized striatal neurodegeneration mimicking the pathological features of Huntington's disease.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Phenyl sulfate is a phenol derivative, containing a sulfuric acid group conjugated to a phenyl group. Phenyl sulfate is a major metabolite of phenol.

Showing 991 - 1000 of 2596 results