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Details

Stereochemistry RACEMIC
Molecular Formula C19H38O4
Molecular Weight 330.5026
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GLYCERYL 1-PALMITATE

SMILES

CCCCCCCCCCCCCCCC(=O)OCC(O)CO

InChI

InChIKey=QHZLMUACJMDIAE-UHFFFAOYSA-N
InChI=1S/C19H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(22)23-17-18(21)16-20/h18,20-21H,2-17H2,1H3

HIDE SMILES / InChI

Molecular Formula C19H38O4
Molecular Weight 330.5026
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Glyceryl-1-palmitate (α-Monopalmitin, Glycerol 1-hexadecanoate) is a member of the chemical class known as Monoacylglycerols. Glycerol 1-hexadecanoate is found in fats and oils. Glycerol 1-hexadecanoate is a minor component of olive oil and other vegetable oil. α-Monopalmitin is a glycerol esterified fatty acid, monoacylglycerol, found in lipid structures such as ceramides. 1-Palmitoylglycerol may be used as a substrate for the identification and differentiation of enzymes that hydrolyze or transfer monoacylglycerols such as neuropathy target esterase(s) and monoacylglycerol acyltransferase(s) (MAG).

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Sample Use Guides

In Vivo Use Guide
Glyceryl-1-palmitate can be used at concentrations up to 12% in cosmetic products
Route of Administration: Topical
In Vitro Use Guide
The IC50 value of Glyceryl-1-palmitate (α-Monopalmitin), isolated from Alocasia macrorrhiza, was 92.28 ug/ml for HePG2 cells, 36.76 ug/ml for Hep-2 cells and 36.24 ug/ml for HCT-116 cells.
Substance Class Chemical
Record UNII
U9H9OM3S75
Record Status Validated (UNII)
Record Version