Details
Stereochemistry | RACEMIC |
Molecular Formula | C19H38O4 |
Molecular Weight | 330.5026 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCCCCCCCCCCCC(=O)OCC(O)CO
InChI
InChIKey=QHZLMUACJMDIAE-UHFFFAOYSA-N
InChI=1S/C19H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(22)23-17-18(21)16-20/h18,20-21H,2-17H2,1H3
Glyceryl-1-palmitate (α-Monopalmitin, Glycerol 1-hexadecanoate) is a member of the chemical class known as Monoacylglycerols. Glycerol 1-hexadecanoate is found in fats and oils. Glycerol 1-hexadecanoate is a minor component of olive oil and other vegetable oil. α-Monopalmitin is a glycerol esterified fatty acid, monoacylglycerol, found in lipid structures such as ceramides. 1-Palmitoylglycerol may be used as a substrate for the identification and differentiation of enzymes that hydrolyze or transfer monoacylglycerols such as neuropathy target esterase(s) and monoacylglycerol acyltransferase(s) (MAG).
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Uptake and metabolism of alpha-monopalmitin by rat lung in vitro. | 1975 Dec |
|
[Studies on the constituents of trichosanthes root. III. Constituents of roots of Trichosanthes bracteata Voigt]. | 1989 Apr |
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Cytotoxic constituents of Diadema setosum. | 2004 Jul |
|
Psychotria viridis: Chemical constituents from leaves and biological properties. | 2017 Apr-Jun |
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/15513825
Glyceryl-1-palmitate can be used at concentrations up to 12% in cosmetic products
Route of Administration:
Topical
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/27497869
The IC50 value of Glyceryl-1-palmitate (α-Monopalmitin), isolated from Alocasia macrorrhiza, was 92.28 ug/ml for HePG2 cells, 36.76 ug/ml for Hep-2 cells and 36.24 ug/ml for HCT-116 cells.
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SUBSTANCE RECORD