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Details

Stereochemistry RACEMIC
Molecular Formula C19H38O4
Molecular Weight 330.5026
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GLYCERYL 1-PALMITATE

SMILES

CCCCCCCCCCCCCCCC(=O)OCC(O)CO

InChI

InChIKey=QHZLMUACJMDIAE-UHFFFAOYSA-N
InChI=1S/C19H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(22)23-17-18(21)16-20/h18,20-21H,2-17H2,1H3

HIDE SMILES / InChI
Glyceryl-1-palmitate (α-Monopalmitin, Glycerol 1-hexadecanoate) is a member of the chemical class known as Monoacylglycerols. Glycerol 1-hexadecanoate is found in fats and oils. Glycerol 1-hexadecanoate is a minor component of olive oil and other vegetable oil. α-Monopalmitin is a glycerol esterified fatty acid, monoacylglycerol, found in lipid structures such as ceramides. 1-Palmitoylglycerol may be used as a substrate for the identification and differentiation of enzymes that hydrolyze or transfer monoacylglycerols such as neuropathy target esterase(s) and monoacylglycerol acyltransferase(s) (MAG).

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Uptake and metabolism of alpha-monopalmitin by rat lung in vitro.
1975 Dec
[Studies on the constituents of trichosanthes root. III. Constituents of roots of Trichosanthes bracteata Voigt].
1989 Apr
Cytotoxic constituents of Diadema setosum.
2004 Jul
Psychotria viridis: Chemical constituents from leaves and biological properties.
2017 Apr-Jun
Patents

Sample Use Guides

Glyceryl-1-palmitate can be used at concentrations up to 12% in cosmetic products
Route of Administration: Topical
The IC50 value of Glyceryl-1-palmitate (α-Monopalmitin), isolated from Alocasia macrorrhiza, was 92.28 ug/ml for HePG2 cells, 36.76 ug/ml for Hep-2 cells and 36.24 ug/ml for HCT-116 cells.
Name Type Language
GLYCERYL 1-PALMITATE
Common Name English
GLYCEROL 1-PALMITATE
Common Name English
GLYCEROL 1-MONOPALMITATE
Common Name English
PALMITIC ACID .ALPHA.-MONOGLYCERIDE
Common Name English
(±)-1-O-HEXADECANOYLGLYCEROL
Systematic Name English
1-GLYCEROL HEXADECANOATE
Common Name English
(±)-1-MONOPALMITIN
Common Name English
DL-1-MONOPALMITIN
Common Name English
(±)-1-HEXADECANOYLGLYCEROL
Systematic Name English
HEXADECANOIC ACID, 2,3-DIHYDROXYPROPYL ESTER
Common Name English
1-MONOHEXADECANOYLGLYCEROL
Systematic Name English
GLYCEROL 1-MONOHEXADECANOATE
Common Name English
NSC-404240
Code English
2,3-DIHYDROXYPROPYL HEXADECANOATE
Systematic Name English
GLYCEROL 3-PALMITATE
Common Name English
1-GLYCERYL MONOHEXADECANOATE
Systematic Name English
2,3-DIHYDROXYPROPYL PALMITATE
Systematic Name English
1-MONOPALMITIN
Common Name English
1-PALMITOYL-RAC-GLYCEROL
Common Name English
.ALPHA.-MONOPALMITIN
Common Name English
PALMITIN, 1-MONO-
Common Name English
Code System Code Type Description
CHEBI
69081
Created by admin on Fri Dec 15 18:58:46 GMT 2023 , Edited by admin on Fri Dec 15 18:58:46 GMT 2023
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NSC
404240
Created by admin on Fri Dec 15 18:58:46 GMT 2023 , Edited by admin on Fri Dec 15 18:58:46 GMT 2023
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PUBCHEM
14900
Created by admin on Fri Dec 15 18:58:46 GMT 2023 , Edited by admin on Fri Dec 15 18:58:46 GMT 2023
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CAS
542-44-9
Created by admin on Fri Dec 15 18:58:46 GMT 2023 , Edited by admin on Fri Dec 15 18:58:46 GMT 2023
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FDA UNII
U9H9OM3S75
Created by admin on Fri Dec 15 18:58:46 GMT 2023 , Edited by admin on Fri Dec 15 18:58:46 GMT 2023
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EPA CompTox
DTXSID00891470
Created by admin on Fri Dec 15 18:58:46 GMT 2023 , Edited by admin on Fri Dec 15 18:58:46 GMT 2023
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ECHA (EC/EINECS)
208-812-9
Created by admin on Fri Dec 15 18:58:46 GMT 2023 , Edited by admin on Fri Dec 15 18:58:46 GMT 2023
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