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Showing 1 - 10 of 72 results

Status:
US Approved Rx (2009)
First approved in 1961

Class (Stereo):
CHEMICAL (RACEMIC)



Glycopyrrolate is a synthetic anticholinergic agent with a quaternary ammonium structure. Glycopyrrolate is a muscarinic competitive antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce salivation with s...
Status:
US Approved Rx (1966)
First approved in 1956

Class (Stereo):
CHEMICAL (ACHIRAL)



LIBRAX® combines in a single capsule formulation the antianxiety action of chlordiazepoxide hydrochloride and the anticholinergic/spasmolytic effects of clidinium bromide. Chlordiazepoxide hydrochloride is a versatile, therapeutic agent of proven val...
Status:
US Approved Rx (2011)
First approved in 1953

Class (Stereo):
CHEMICAL (ABSOLUTE)



Methscopolamine bromide is an anticholinergic agent used along with other medications to treat peptic ulcers by reducing stomach acid secretion. Methscopolamine is also commonly used as a drying agent, to dry up post-nasal drip, in cold, irritable bo...
Status:
US Approved OTC
First approved in 1961

Class (Stereo):
CHEMICAL (ACHIRAL)



Bismuth aluminate is an antacid drug. The good therapeutic results are due to a coating effect providing a local antipepsin action at the site of the ulcer is an interesting possibility. Inorganic bismuth derivatives have good antibacterial propertie...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)



Irsogladine, a mucosal protective drug, was developed in Japan for the treatment of peptic ulcer disease and acute gastritis. Irsogladine increases intracellular cyclic adenosine 3',5'-monophosphate content via non-selective inhibition of phosphodies...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)



Nastorazepide (Z-360) is a selective, orally available, gastrin/cholecystokinin 2 (CCK-2) receptor antagonist with potential antineoplastic activity. Z-360 binds to the gastrin/CCK-2 receptor, thereby preventing receptor activation by gastrin, a pept...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)



Esaprazole, also known as hexaprazole, was developed in the 1980s as a drug for the treatment of gastric and duodenal ulcers. Esaprazole exerts a dose-dependent cytoprotective effect on the gastric mucosa in man. It was shown to have a dose-dependent...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Trithiozine is an alkoxythiobenzamide said to have antisecretory and tranquillising properties without anticholinergic, antihistaminic, or ganglion-blocking effects. Trithiozine in animal studies proved to have a marked anti-secretory and anti-ulcer ...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Lozilurea (N' -3-chlorobenzyl-N'-ethylurea, ITA 312) has shown marked anti-ulcer activity. It has shown itself to be active against chemically and neurogenically induced gastric and duodenal lesions in various experimental animal models. It has no ma...
N-Ethyl-3-piperidyl benzilate (JB-318) is an anticholinergic drug. It is a potent hallucinogenic agent. JB-318 is a psychotomimetic, it has an antitremor action in patients with Parkinson disease.