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Showing 1 - 10 of 41 results

Status:
US Approved Rx (2022)
First approved in 1963

Class (Stereo):
CHEMICAL (ACHIRAL)



Diazepam is a benzodiazepine first discovered at Hoffman-La Roche in the late 1950s. Diazepam was approved by FDA for the treatment of anxiety disorders as well as for such conditions as skeletal muscle spasm, alcohol withdrawal syndrom and convulsion...
Status:
US Approved Rx (2023)
First approved in 1958

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Chlorzoxazone is a centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain where it inhibits multisyna...
Status:
US Approved Rx (1979)
First approved in 1957

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

Methocarbamol is a central muscle relaxant for skeletal muscles, used to treat spasms. It is structurally related to guaifenesin. Methocarbamol's exact mechanism of causing skeletal muscle relaxation is unknown. It is thought to work centrally, perha...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Nafomine is the muscle relaxant. It was tested on lower extremity spasms in spinal cord injuries.
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)

Targets:


Fenamole is a muscle relaxant. It is effectively inhibits muscle spasms at good levels for a four hours and at significant levels for six hours. Clinical benefits were derived in patients with spasticity-spasm for periods up to 24 hours after a singl...
SL651498 was identified as a drug development candidate from a research program designed to discover subtype-selective GABA(A) receptor agonists for the treatment of generalized anxiety disorder and muscle spasms. SL651498 displayed high affinity for...
Beta-erythroidine is an organic heterotetracyclic indole alkaloid isolated from the seeds and other parts of Erythrina species. A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic u...
Status:
US Previously Marketed
First approved in 1965

Class (Stereo):
CHEMICAL (RACEMIC)



Chlorphenesin carbamate (Maolate, Musil) is a centrally acting muscle relaxant used to treat muscle pain and spasms. Сhlorphenesin acts in the central nervous system (CNS) rather than directly on skeletal muscle. It also has antifungal and some antib...
Status:
US Previously Marketed
First approved in 1961

Class (Stereo):
CHEMICAL (RACEMIC)

Conditions:

Mephenoxalone is an oxazolidinone compound. It is a skeletal muscle relaxant as well as anxiolytic. Mephenoxalone is indicated for the treatment of muscle spasms.
Status:
US Previously Marketed
First approved in 1958

Class (Stereo):
CHEMICAL (RACEMIC)

Conditions:

Chlormezanone (TRANCOPAL®) is a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm. It binds to central benzodiazepine receptors which interact allosterically with GABA recepto...