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Details

Stereochemistry RACEMIC
Molecular Formula C11H13NO4
Molecular Weight 223.2252
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MEPHENOXALONE

SMILES

COC1=C(OCC2CNC(=O)O2)C=CC=C1

InChI

InChIKey=ZMNSRFNUONFLSP-UHFFFAOYSA-N
InChI=1S/C11H13NO4/c1-14-9-4-2-3-5-10(9)15-7-8-6-12-11(13)16-8/h2-5,8H,6-7H2,1H3,(H,12,13)

HIDE SMILES / InChI

Molecular Formula C11H13NO4
Molecular Weight 223.2252
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Mephenoxalone is an oxazolidinone compound. It is a skeletal muscle relaxant as well as anxiolytic. Mephenoxalone is indicated for the treatment of muscle spasms.

CNS Activity

Originator

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
DORSIFLEX

Cmax

ValueDoseCo-administeredAnalytePopulation
2849 ng/mL
200 mg single, oral
MEPHENOXALONE plasma
Homo sapiens

AUC

ValueDoseCo-administeredAnalytePopulation
16274 ng × h/mL
200 mg single, oral
MEPHENOXALONE plasma
Homo sapiens

T1/2

ValueDoseCo-administeredAnalytePopulation
2.77 h
200 mg single, oral
MEPHENOXALONE plasma
Homo sapiens

Overview

CYP3A4CYP2C9CYP2D6hERG

OverviewOther

Other InhibitorOther SubstrateOther Inducer

Drug as victim

PubMed

Sample Use Guides

In Vivo Use Guide
Adult: 200-400 mg tid.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
CZ87T54W8W
Record Status Validated (UNII)
Record Version