NAFOMINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H13NO
Molecular Weight	187.2377
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of NAFOMINE

Structure Search

SMILES

CC1=CC=C2C=CC=CC2=C1CON

InChI

InChIKey=DSBSLDVRDBLLFL-UHFFFAOYSA-N

InChI=1S/C12H13NO/c1-9-6-7-10-4-2-3-5-11(10)12(9)8-14-13/h2-7H,8,13H2,1H3

HIDE SMILES / InChI

Molecular Formula	C12H13NO
Molecular Weight	187.2377
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5161653
Curator's Comment: description was created based on several sources, including: https://www.google.ch/patents/US6323236

Nafomine is the muscle relaxant. It was tested on lower extremity spasms in spinal cord injuries.

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Muscle spasm 41 Sources: https://www.ncbi.nlm.nih.gov/pubmed/5161653	Primary		Not Provided 511	Unknown Approved Use Unknown

PubMed

PubMed

Title	Date	PubMed
Effects of nafomine malate on lower extremity spasms in spinal cord injuries (a preliminary study).	1971	5161653

Patents

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Wed Apr 02 06:51:47 GMT 2025` Edited by `admin` on `Wed Apr 02 06:51:47 GMT 2025`
Record UNII	26C7FUA5S7
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NAFOMINE

Official Name

English

nafomine [INN]

Preferred Name

English

O-((2-METHYL-1-NAPHTHYL)METHYL)HYDROXYLAMINE

Systematic Name

English

Code System Code Type Description

FDA UNII

26C7FUA5S7

Created by admin on Wed Apr 02 06:51:47 GMT 2025 , Edited by admin on Wed Apr 02 06:51:47 GMT 2025

PRIMARY

NCI_THESAURUS

C166545

Created by admin on Wed Apr 02 06:51:47 GMT 2025 , Edited by admin on Wed Apr 02 06:51:47 GMT 2025

PRIMARY

EPA CompTox

DTXSID40866122

Created by admin on Wed Apr 02 06:51:47 GMT 2025 , Edited by admin on Wed Apr 02 06:51:47 GMT 2025

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CAS

46263-35-8

Created by admin on Wed Apr 02 06:51:47 GMT 2025 , Edited by admin on Wed Apr 02 06:51:47 GMT 2025

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PUBCHEM

31749

Created by admin on Wed Apr 02 06:51:47 GMT 2025 , Edited by admin on Wed Apr 02 06:51:47 GMT 2025

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EVMPD

SUB09125MIG

Created by admin on Wed Apr 02 06:51:47 GMT 2025 , Edited by admin on Wed Apr 02 06:51:47 GMT 2025

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SMS_ID

100000084435

Created by admin on Wed Apr 02 06:51:47 GMT 2025 , Edited by admin on Wed Apr 02 06:51:47 GMT 2025

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INN

2860

Created by admin on Wed Apr 02 06:51:47 GMT 2025 , Edited by admin on Wed Apr 02 06:51:47 GMT 2025

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ChEMBL

CHEMBL2110690

Created by admin on Wed Apr 02 06:51:47 GMT 2025 , Edited by admin on Wed Apr 02 06:51:47 GMT 2025

PRIMARY

Related Record Type Details


					6GY9OKU6VW

NAFOMINE MALATE

SALT/SOLVATE -> PARENT

Related Record Type Details


					26C7FUA5S7

NAFOMINE

ACTIVE MOIETY