U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 51 - 60 of 234 results

Status:
Possibly Marketed Outside US
First approved in 1989
Source:
Bio-Groom Lido-Med Veterinary Strength by Bio-Derm Laboratories Inc.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Status:
Possibly Marketed Outside US
Source:
Canada:ENROFLOXACIN
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Enrofloxacin was developed by Bayer for the treatment of broad spectrum of bacterial infections in animals (cats and dogs). The drug exerts its action by inhibiting DNA Topoisomerase II (Gyrase) and DNA Topoisomerase IV (Topo IV), two major bacterial topoisomerase. Enrofloxacin was shown to be metabolized to ciprofloxacin and may cross the blood brain barrier in the animals.
Status:
Possibly Marketed Outside US
Source:
part333E
Source URL:
First approved in 1960

Class (Stereo):
CHEMICAL (ACHIRAL)



Brilliant green is a synthetic dye. Brilliant green inhibits the growth of gram-positive bacterias and thus has antibacterial properties. It is broadly used as a topical antiseptic (in form of cutaneous solution), especially in Russia and Eastern Europe.
Status:
Possibly Marketed Outside US
Source:
Japan:Lenampicillin Hydrochloride
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



Lenampicillin is a prodrug of ampicillin that inhibits bacterial penicillin binding proteins (transpeptidase) and thus is effective against a wide range of bacterial infections. The drug was developed and marketed in Japan (Takacillin, Varacillin), however its current marketing status is unknown and supposed to be discontinued.
Status:
Possibly Marketed Outside US
Source:
Japan:Thiamphenicol
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



Thiamphenicol is a broad-spectrum antibiotic, which is active against gram-positive and gram-negative organisms. The drug is marketed in Asia and Latin America for the treatment of various infections, including sexually transmitted diseases. As many phenicols, thiamphenicol inhibits the protein synthesis in bacterias by binding to 23S ribosomal subunit. In Europe and USA the drug is used in a veterinary practice.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ABSOLUTE)



Cefalonium is a 1st generation cephalosporin with a broad spectrum of actvity against Gram-positive and Gram-negative bacterias. The drug inhibits the bacterial cell wall synthesis by binding to penicillin binding proteins. Cefalonium is approved for routine dry cow therapy to treat existing sub-clinical infections and to prevent new infections which occur during the dry period.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)



Sulfaperine is a long-acting sulfonamide antibiotic.
Olamufloxacin (HSR-903) is an oral fluoroquinolone antimicrobial agent which has been reported to have a potent activity against respiratory pathogens, such as Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, Klebsiella pneumoniae, Staphylococcus aureus, Chlamydia spp. and Legionella spp., as well. Olamufloxacin inhibits DNA gyrase from the susceptible and resistant bacterial strains. It has been shown that olamufloxacin possesses a more potent antibacterial activity against potential respiratory pathogens compared with other quinolone derivatives. An oral formulation of olamufloxacin was undergoing phase III for Bacterial infections in Japan (Discontinued).
Status:
Possibly Marketed Outside US
Source:
Japan:Sulfametomidine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Sulfametomidine (or sulfamethomidine) is a sulfonamide antibacterial with a broad spectrum of activity; it’s an inhibitor of dihydrofolate reductase.
Status:
Possibly Marketed Outside US
Source:
Japan:Cefroxadine
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Cefroxadine is an antibiotic developed for the treatment of bacterial infectious diseases caused by gram-negative and gram-positive organisms. The information about drug status is unavailable and is supposed to be "discontinued", however it may be manufactured in Italy by Novartis.