BRILLIANT GREEN CATION

Details

Stereochemistry	ACHIRAL
Molecular Formula	C27H33N2
Molecular Weight	385.5643
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	1

SHOW SMILES / InChI

Structure Search

SMILES

CCN(CC)C1=CC=C(C=C1)C(C2=CC=CC=C2)=C3C=CC(C=C3)=[N+](CC)CC

InChI

InChIKey=HXCILVUBKWANLN-UHFFFAOYSA-N

InChI=1S/C27H33N2/c1-5-28(6-2)25-18-14-23(15-19-25)27(22-12-10-9-11-13-22)24-16-20-26(21-17-24)29(7-3)8-4/h9-21H,5-8H2,1-4H3/q+1

HIDE SMILES / InChI

Molecular Formula	C27H33N2
Molecular Weight	385.5643
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.valentis.com/uploads/shop/docs/66_0115e26e32e821ae73e9ef60a3270328.pdf

Brilliant green is a synthetic dye. Brilliant green inhibits the growth of gram-positive bacterias and thus has antibacterial properties. It is broadly used as a topical antiseptic (in form of cutaneous solution), especially in Russia and Eastern Europe.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Bacteial cells growth 2 Target ID: Bacteial cells growth Sources: https://www.ncbi.nlm.nih.gov/pubmed/13416511	Inhibitor 8297

Conditions

Condition	Modality	Targets	Highest Phase	Product
Bacterial infections 234 Sources: https://www.ncbi.nlm.nih.gov/pubmed/17866691	Preventing		Approved 8429	BRILLIANT GREEN Approved Use Brilliant green is used as antiseptic for skin abrasions and scratches; to mark the intended section place before the surgical operation.
Umbilical cord area infection in newborn 2 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=44e0306a-2c14-4cc3-9ac1-218c0c8b15a0	Preventing		Approved 8429	KERR 100 TRIPLE DYE Approved Use Aids in the prevention of infection in the umbilical cord area of newborn.

PubMed

Title	Date	PubMed
A Note on the Value of Brilliant Green as an Antiseptic.	1917 Jun 30	20768638
Use of crystal violet or brilliant green dyes for the determination of Salmonellae in dried food products.	1960 Dec	13729626
EFFECT OF VARIOUS CONCENTRATIONS OF BRILLIANT GREEN AND BILE SALTS ON SALMONELLAE AND OTHER MICROORGANISMS.	1965 Jan	14264851
Effect of brilliant green on the motility of Salmonellae and other selected microorganisms.	1969 Oct	4983955
Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.	2011 Jul 14	21599003

Patents

Sample Use Guides

In Vivo Use Guide

Apply to the affected area using cotton swabs or gauze pads.

Route of Administration: Topical

In Vitro Use Guide

Staphylococcus aureus strain was treated with brilliant green at final concentration of 8.8*10(-4) M. At this concentration the drug inhibited the cells growth by 50%.

Substance Class	Chemical Created by `admin` on `Sat Dec 16 01:38:29 GMT 2023` Edited by `admin` on `Sat Dec 16 01:38:29 GMT 2023`
Record UNII	S85JD8CLBH
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BRILLIANT GREEN CATION

Common Name

English

ETHANAMINIUM, N-(4-((4-(DIETHYLAMINO)PHENYL)PHENYLMETHYLENE)-2,5-CYCLOHEXADIEN-1-YLIDENE)-N-ETHYL-

Systematic Name

English

BRILLIANT GREEN, FREE FORM

Common Name

English

BRILLIANT GREEN ION

Common Name

English

Code System Code Type Description

DAILYMED

S85JD8CLBH