BRILLIANT GREEN CATION

Details

Stereochemistry	ACHIRAL
Molecular Formula	C27H33N2
Molecular Weight	385.5643
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	1

SHOW SMILES / InChI

SMILES

CCN(CC)C1=CC=C(C=C1)C(C2=CC=CC=C2)=C3C=CC(C=C3)=[N+](CC)CC

InChI

InChIKey=HXCILVUBKWANLN-UHFFFAOYSA-N

InChI=1S/C27H33N2/c1-5-28(6-2)25-18-14-23(15-19-25)27(22-12-10-9-11-13-22)24-16-20-26(21-17-24)29(7-3)8-4/h9-21H,5-8H2,1-4H3/q+1

HIDE SMILES / InChI

Molecular Formula	C27H33N2
Molecular Weight	385.5643
Charge	1
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description

Brilliant green is a synthetic dye. Brilliant green inhibits the growth of gram-positive bacterias and thus has antibacterial properties. It is broadly used as a topical antiseptic (in form of cutaneous solution), especially in Russia and Eastern Europe.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Bacteial cells growth 2	Inhibitor 8,504

Conditions

Condition	Modality	Targets	Highest Phase	Product
Bacterial infections 235	Preventing		Approved 8,583	BRILLIANT GREEN
Umbilical cord area infection in newborn 2	Preventing		Approved 8,583	KERR 100 TRIPLE DYE

PubMed

Show entries

Title	Date	PubMed
A Note on the Value of Brilliant Green as an Antiseptic.	1917 Jun 30	20768638
Use of crystal violet or brilliant green dyes for the determination of Salmonellae in dried food products.	1960 Dec	13729626
EFFECT OF VARIOUS CONCENTRATIONS OF BRILLIANT GREEN AND BILE SALTS ON SALMONELLAE AND OTHER MICROORGANISMS.	1965 Jan	14264851
Effect of brilliant green on the motility of Salmonellae and other selected microorganisms.	1969 Oct	4983955
Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.	2011 Jul 14	21599003

Showing 1 to 5 of 5 entries

Previous1Next

Patents

Sample Use Guides

In Vivo Use Guide

Apply to the affected area using cotton swabs or gauze pads.

Route of Administration: Topical

In Vitro Use Guide

Staphylococcus aureus strain was treated with brilliant green at final concentration of 8.8*10(-4) M. At this concentration the drug inhibited the cells growth by 50%.

Substance Class	Chemical
Record UNII	S85JD8CLBH
Record Status	`Validated (UNII)`
Record Version

Show entries

Name

Type

Language

BRILLIANT GREEN ION

Preferred Name

English

BRILLIANT GREEN CATION

Common Name

English

ETHANAMINIUM, N-(4-((4-(DIETHYLAMINO)PHENYL)PHENYLMETHYLENE)-2,5-CYCLOHEXADIEN-1-YLIDENE)-N-ETHYL-

Systematic Name

English

BRILLIANT GREEN, FREE FORM

Common Name

English

Showing 1 to 4 of 4 entries

Previous1Next

Show entries

Code System

Code

Type

Description

DAILYMED

S85JD8CLBH

PRIMARY

ECHA (EC/EINECS)

242-088-5

PRIMARY

RXCUI

1546367

PRIMARY

RxNorm

FDA UNII

S85JD8CLBH

PRIMARY

PUBCHEM

12450

PRIMARY

Showing 1 to 5 of 8 entries

Previous1 2Next

Show entries

Related Record

Type

Details


					S85JD8CLBH

BRILLIANT GREEN CATION

ACTIVE MOIETY

Showing 1 to 1 of 1 entries

Previous1Next