SULFAMETOMIDINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H14N4O3S
Molecular Weight	294.33
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC(NS(=O)(=O)C2=CC=C(N)C=C2)=NC(C)=N1

InChI

InChIKey=QKLSCPPJEVXONT-UHFFFAOYSA-N

InChI=1S/C12H14N4O3S/c1-8-14-11(7-12(15-8)19-2)16-20(17,18)10-5-3-9(13)4-6-10/h3-7H,13H2,1-2H3,(H,14,15,16)

HIDE SMILES / InChI

Molecular Formula	C12H14N4O3S
Molecular Weight	294.33
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://drugs-about.com/ing/sulfametomidine.html
Curator's Comment: description was created based on several sources, including http://datagovtw.com/fda.php?id=%E5%85%A7%E8%A1%9B%E8%97%A5%E8%A3%BD%E5%AD%97%E7%AC%AC016294%E8%99%9F

Sulfametomidine (or sulfamethomidine) is a sulfonamide antibacterial with a broad spectrum of activity; it’s an inhibitor of dihydrofolate reductase.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Bacterial dihydrofolate reductase 5 Target ID: CHEMBL2364669 Sources: http://apps.who.int/iris/bitstream/10665/77376/1/9789241504485_eng.pdf	Inhibitor 8297

Conditions

Condition	Modality	Targets	Highest Phase	Product
Bacterial infections 234 Sources: http://datagovtw.com/fda.php?id=%E5%85%A7%E8%A1%9B%E8%97%A5%E8%A3%BD%E5%AD%97%E7%AC%AC016294%E8%99%9F	Curative		Approved 8429	METHOFADIN INJECTION Approved Use Unknown

PubMed

Title	Date	PubMed
Acetylation phenotype status in a Bangladeshi population and its comparison with that of other Asian population data.	2004 Sep	15334622
Comparative therapeutic effect of toltrazuril, sulphadimidine and amprolium on Eimeria bovis and Eimeria zuernii given at different times following infection in buffalo calves (Bubalus bubalis).	2008 Apr 17	18262668

Patents

Sample Use Guides

In Vivo Use Guide

initially 2 mg. subsequently 24 hour intervals in an average total dose of 6.3 mg.

Route of Administration: Other

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:13:51 GMT 2023` Edited by `admin` on `Sat Dec 16 16:13:51 GMT 2023`
Record UNII	940ZL3AHKB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SULFAMETOMIDINE

Official Name

English

SULFAMETHOMIDINE [MI]

Common Name

English

Sulfametomidine [WHO-DD]

Common Name

English

sulfametomidine [INN]

Common Name

English

SULFAMETOMIDINE [JAN]

Common Name

English

Classification Tree Code System Code

WHO-ATC

J01ED03