HUMAN INTERLEUKIN-6

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 03:46:26 UTC 2023` Edited by `admin` on `Sat Dec 16 03:46:26 UTC 2023`
Protein Type	CYTOKINE
Protein Sub Type	INTERLEUKINS
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	4O4QWG0B3C
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

HUMAN INTERLEUKIN-6

Common Name

English

HUMAN INTERFERON BETA-2

Common Name

English

IL-6

Common Name

English

Interleukin-6 [WHO-DD]

Common Name

English

INTERLEUKIN-6 HUMAN

Common Name

English

INTERFERON BETA-2 HUMAN

Common Name

English

INTERLEUKIN-6

Common Name

English

IL6

Common Name

English

HUMAN B-CELL STIMULATORY FACTOR 2

Common Name

English

INTERLEUKIN-6, HUMAN

Common Name

English

Classification Tree Code System Code

LOINC

49732-1

Created by admin on Sat Dec 16 03:46:26 UTC 2023 , Edited by admin on Sat Dec 16 03:46:26 UTC 2023

NCI_THESAURUS

C593

Created by admin on Sat Dec 16 03:46:26 UTC 2023 , Edited by admin on Sat Dec 16 03:46:26 UTC 2023

Code System Code Type Description

FDA UNII

4O4QWG0B3C

Created by admin on Sat Dec 16 03:46:26 UTC 2023 , Edited by admin on Sat Dec 16 03:46:26 UTC 2023

PRIMARY

RXCUI

1367185

Created by admin on Sat Dec 16 03:46:26 UTC 2023 , Edited by admin on Sat Dec 16 03:46:26 UTC 2023

ALTERNATIVE

NCI_THESAURUS

C591

Created by admin on Sat Dec 16 03:46:26 UTC 2023 , Edited by admin on Sat Dec 16 03:46:26 UTC 2023

PRIMARY

NCIT

RXCUI

1427163

Created by admin on Sat Dec 16 03:46:26 UTC 2023 , Edited by admin on Sat Dec 16 03:46:26 UTC 2023

PRIMARY

EVMPD

SUB32791

Created by admin on Sat Dec 16 03:46:26 UTC 2023 , Edited by admin on Sat Dec 16 03:46:26 UTC 2023

PRIMARY

From	To
1_43	1_49
1_72	1_82

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_44

Related Record Type Details


					AN3Y2B4SX4

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					KP04MH1JTT

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					F46A50C4CW

INTERLEUKIN-6 RECEPTOR SUBUNIT BETA

AGONIST -> TARGET

Comments:

Forms hexameric signaling complex with IL-6 and IL-6 receptor. Signaling component of the hexameric complex.

Amount:


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Amount:


					SMV73KW49C

INHIBITOR OF EXPRESSION->TARGET

Comments:

Increased expression of PRG4 mRNA in tendons treated with rabPXL01 in HA, but not in tendon sheaths. In addition, treatment with rabPXL01 in HA led to repression of the mRNA levels for the pro-inflammatory mediators interleukin (IL)-1β, IL-6, and IL-8 in tendon sheaths.

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					2NHW9AKY9C

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					FZ7798X3IR

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INHIBITOR -> TARGET

Amount:


					4S38Z8RA9O

INHIBITOR -> TARGET

Comments:

Binds to IL6 prevents formation of activating complex.

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL