INTERLEUKIN-6 RECEPTOR SUBUNIT BETA

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 18:01:29 GMT 2025` Edited by `admin` on `Tue Apr 01 18:01:29 GMT 2025`
Protein Type	RECEPTOR
Protein Sub Type	INTERLEUKINS
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	F46A50C4CW
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

INTERLEUKIN-6 RECEPTOR SUBUNIT BETA

Common Name

English

CD130

Preferred Name

English

IL-6 receptor subunit beta

Common Name

English

IL-6RB

Common Name

English

GP130

Common Name

English

IL-6R-beta

Common Name

English

Membrane glycoprotein 130

Common Name

English

Glycoprotein 130

Common Name

English

Interleukin-6 signal transducer

Common Name

English

Oncostatin-M receptor subunit alpha

Common Name

English

CDw130

Common Name

English

IL-6R subunit beta

Common Name

English

Code System Code Type Description

UNIPROT

P40189

Created by admin on Tue Apr 01 18:01:29 GMT 2025 , Edited by admin on Tue Apr 01 18:01:29 GMT 2025

PRIMARY

FDA UNII

F46A50C4CW

Created by admin on Tue Apr 01 18:01:29 GMT 2025 , Edited by admin on Tue Apr 01 18:01:29 GMT 2025

PRIMARY

From	To
1_6	1_32
1_26	1_81
1_112	1_122
1_150	1_160
1_436	1_444

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_21
N	1_61
N	1_109
N	1_135
N	1_205
N	1_357
N	1_361
N	1_368
N	1_531
N	1_542

Related Record Type Details


					4O4QWG0B3C

HUMAN INTERLEUKIN-6

TARGET -> AGONIST

Comments:

Forms hexameric signaling complex with IL-6 and IL-6 receptor. Signaling component of the hexameric complex.

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_639] [1_645] [1_760] [1_767] [1_807] [1_817]				DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL

Molecular Formula	CHEMICAL