U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Mon Mar 31 21:25:37 GMT 2025
Edited
by admin
on Mon Mar 31 21:25:37 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1|KAPPA
Sequence Origin HUMANIZED RABBIT
Sequence Type COMPLETE
Record UNII
4S38Z8RA9O
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CLAZAKIZUMAB
INN   USAN   WHO-DD  
USAN   INN  
Official Name English
ALD-518
Preferred Name English
ALD518
Code English
Clazakizumab [WHO-DD]
Common Name English
CLAZAKIZUMAB (Aglycosylated IGG1 humanized rabbit antibody directed against IL6)
Common Name English
clazakizumab [INN]
Common Name English
CLAZAKIZUMAB [USAN]
Common Name English
RECOMBINANT HUMANIZED CHIMERIC HUMAN-LEPORINE IgG1 KAPPA ANTI-INTERLEUKIN 6 MONOCLONAL ANTIBODY
Common Name English
BMS-945429
Code English
Classification Tree Code System Code
FDA ORPHAN DRUG 612317
Created by admin on Mon Mar 31 21:25:37 GMT 2025 , Edited by admin on Mon Mar 31 21:25:37 GMT 2025
Code System Code Type Description
CAS
1236278-28-6
Created by admin on Mon Mar 31 21:25:37 GMT 2025 , Edited by admin on Mon Mar 31 21:25:37 GMT 2025
PRIMARY
INN
9599
Created by admin on Mon Mar 31 21:25:37 GMT 2025 , Edited by admin on Mon Mar 31 21:25:37 GMT 2025
PRIMARY
USAN
YY-119
Created by admin on Mon Mar 31 21:25:37 GMT 2025 , Edited by admin on Mon Mar 31 21:25:37 GMT 2025
PRIMARY
DRUG BANK
DB12849
Created by admin on Mon Mar 31 21:25:37 GMT 2025 , Edited by admin on Mon Mar 31 21:25:37 GMT 2025
PRIMARY
SMS_ID
100000142906
Created by admin on Mon Mar 31 21:25:37 GMT 2025 , Edited by admin on Mon Mar 31 21:25:37 GMT 2025
PRIMARY
NCI_THESAURUS
C82359
Created by admin on Mon Mar 31 21:25:37 GMT 2025 , Edited by admin on Mon Mar 31 21:25:37 GMT 2025
PRIMARY
EVMPD
SUB117542
Created by admin on Mon Mar 31 21:25:37 GMT 2025 , Edited by admin on Mon Mar 31 21:25:37 GMT 2025
PRIMARY
WIKIPEDIA
BMS-945429
Created by admin on Mon Mar 31 21:25:37 GMT 2025 , Edited by admin on Mon Mar 31 21:25:37 GMT 2025
PRIMARY
FDA UNII
4S38Z8RA9O
Created by admin on Mon Mar 31 21:25:37 GMT 2025 , Edited by admin on Mon Mar 31 21:25:37 GMT 2025
PRIMARY
ChEMBL
CHEMBL2108589
Created by admin on Mon Mar 31 21:25:37 GMT 2025 , Edited by admin on Mon Mar 31 21:25:37 GMT 2025
PRIMARY
From To
1_22 1_95
1_147 1_203
1_264 1_324
1_370 1_428
2_22 2_95
2_147 2_203
2_264 2_324
2_370 2_428
3_23 3_88
3_137 3_197
4_23 4_88
4_137 4_197
1_223 3_217
2_223 4_217
1_229 2_229
1_232 2_232
Related Record Type Details
HUMAN INTERLEUKIN-6
TARGET -> INHIBITOR
Binds to IL6 prevents formation of activating complex.
Related Record Type Details
CLAZAKIZUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:ESTIMATE CHEMICAL
NIH
NCATS
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