U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 18:21:06 UTC 2021
Edited
by admin
on Sat Jun 26 18:21:06 UTC 2021
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
I031V2H011
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
TOCILIZUMAB
DASH   EMA EPAR   INN   MART.   MI   USAN   VANDF   WHO-DD  
USAN   INN  
Official Name English
TOCILIZUMAB [EMA EPAR]
Common Name English
TOCILIZUMAB [INN]
Common Name English
MRA
Common Name English
TOCILIZUMAB (GENETICAL RECOMBINATION)
JAN  
Official Name English
ROACTEMRA
Common Name English
TOCILIZUMAB [WHO-DD]
Common Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN INTERLEUKIN 6 RECEPTOR) (HUMAN-MOUSE MONOCLONAL MRA HEAVY CHAIN), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL MRA .KAPPA.-CHAIN, DIMER
Common Name English
R-1569
Code English
ATLIZUMAB
Common Name English
TOCILIZUMAB [MART.]
Common Name English
RHPM-1
Code English
TOCILIZUMAB [PURPLE BOOK, CDER]
Common Name English
TOCILIZUMAB [USAN]
Common Name English
TOCILIZUMAB [MI]
Common Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN INTERLEUKIN 6 RECEPTOR) (HUMAN-MOUSE MONOCLONAL MRA HEAVY CHAIN), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL MRA .KAPPA.-CHAIN, DIMER
Common Name English
RG-1569
Code English
ACTEMRA
Brand Name English
RO-4877533
Code English
TOCILIZUMAB [VANDF]
Common Name English
Classification Tree Code System Code
NDF-RT N0000190480
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
LIVERTOX 973
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
EMA ASSESSMENT REPORTS ROACTEMRA (AUTHORIZED: ARTHRITIS, JUVENILE RHEUMATOID)
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
NCI_THESAURUS C20401
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
WHO-ATC L04AC07
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
FDA ORPHAN DRUG 589317
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
FDA ORPHAN DRUG 367812
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
EMA ASSESSMENT REPORTS ROACTEMRA (AUTHORIZED: ARTHRITIS, RHEUMATOID)
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
FDA ORPHAN DRUG 436114
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
WHO-VATC QL04AC07
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
FDA ORPHAN DRUG 381212
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
Code System Code Type Description
INN
8394
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
PRIMARY
NCI_THESAURUS
C84217
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
PRIMARY
DRUG CENTRAL
4933
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
PRIMARY
JAPANESE REVIEW
ACTEMRA
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
PRIMARY APPROVED APRIL 2008
FDA UNII
I031V2H011
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
PRIMARY
WIKIPEDIA
TOCILIZUMAB
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
PRIMARY
CAS
375823-41-9
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
PRIMARY
IUPHAR
6881
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
PRIMARY
ChEMBL
CHEMBL1237022
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
PRIMARY
MERCK INDEX
M10921
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
PRIMARY Merck Index
NDF-RT
N0000190478
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
PRIMARY Interleukin 6 Receptor Antagonists [MoA]
MESH
C502936
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
PRIMARY
DRUG BANK
DB06273
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
PRIMARY
RXCUI
612865
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
PRIMARY RxNorm
LACTMED
Tocilizumab
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
PRIMARY
EVMPD
SUB20313
Created by admin on Sat Jun 26 18:21:06 UTC 2021 , Edited by admin on Sat Jun 26 18:21:06 UTC 2021
PRIMARY
From To
1_22 1_96
1_146 1_202
1_222 3_214
1_228 2_228
1_231 2_231
1_263 1_323
1_369 1_427
2_22 2_96
2_146 2_202
2_222 4_214
2_263 2_323
2_369 2_427
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_299
N 2_299
Related Record Type Details
TARGET -> INHIBITOR
TARGET -> INHIBITOR
SUB_CONCEPT->SUBSTANCE
BIOSIMILAR -> PARENT
SUB_CONCEPT->SUBSTANCE
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT(ESTIMATE) CHEMICAL
Biological Half-life PHARMACOKINETIC