Ramipril isopropyl ester is the proline-containing impurity of ramipril, labelled as ramipril Impurity B. Ramipril is an angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure (hypertension) and congestive heart failure.

Ramipril, (-)- is less active R-enantiomer than S-enantiomer. S-ramipril is angiotensin-converting enzyme (ACE) inhibitor, which is used for the treatment of hypertension.

(2S,3AS,6AS)-1-((2R)-2-(((1S)-1-(Ethoxycarbonyl)-3-phenylpropyl)amino)propanoy)octahydrocyclopenta(B)pyrrole-2-carboxylic acid is one of many isomers of ramipril and is known as Impurity I. Ramipril is an angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure (hypertension) and congestive heart failure.

(R,S,S,S,S)-Ramipril Epimer is one of many isomers of ramipril and is known as Impurity H. Ramipril is an angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure (hypertension) and congestive heart failure.

Ramipril methyl ester is the proline-containing impurity of ramipril, labelled as ramipril Impurity A. It is one of the four qualified impurities. Impurity A is the manufacture process impurity. Ramipril is an angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure (hypertension) and congestive heart failure.

(2R,3AR,6AR)-1-((2S)-2-(((1S)-1-(ethoxycarbonyl)-3-phenylpropyl)amino)propanoyl)octahydrocyclopenta(B)pyrole-2-carboxylic acid is one of many isomers of ramipril and is known as Impurity N. Ramipril is an angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure (hypertension) and congestive heart failure.

Ramipril (sold under the brand name Altace ) is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitors. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Ramipril is indicated for the treatment of hypertension, to lower blood pressure; also used to reduce the risk of myocardial infarction, stroke, or death from cardiovascular causes; in addition, this drug is used to reduce the rate of death, myocardial infarction and stroke in individuals at high risk of cardiovascular events.