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Details

Stereochemistry ABSOLUTE
Molecular Formula C23H32N2O5
Molecular Weight 416.5106
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of RAMIPRIL, (-)-

SMILES

CCOC(=O)[C@@H](CCC1=CC=CC=C1)N[C@H](C)C(=O)N2[C@@H]3CCC[C@@H]3C[C@@H]2C(O)=O

InChI

InChIKey=HDACQVRGBOVJII-YHUYVZNPSA-N
InChI=1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17-,18-,19-,20-/m1/s1

HIDE SMILES / InChI

Description

Ramipril, (-)- is less active R-enantiomer than S-enantiomer. S-ramipril is angiotensin-converting enzyme (ACE) inhibitor, which is used for the treatment of hypertension.

Approval Year

Unknown
149124
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Biosensors for the enantioselective analysis of S-enalapril and S-ramipril.
1998-11

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
RAMIPRIL, (-)-
Common Name English
ENANTIOMER OF RAMIPRIL
Preferred Name English
(2R,3AR,6AR)-1-((2R)-2-(((1R)-1-(ETHOXYCARBONYL)-3-PHENYLPROPYL)AMINO)PROPANOYL)OCTAHYDROCYCLOPENTA(B)PYRROLE-2-CARBOXYLIC ACID
Systematic Name English
ENT-RAMIPRIL
Common Name English
RAMIPRIL IMPURITY J [EP IMPURITY]
Common Name English
Code System Code Type Description
FDA UNII
5COV0OAU1T
Created by admin on Mon Mar 31 22:06:50 GMT 2025 , Edited by admin on Mon Mar 31 22:06:50 GMT 2025
PRIMARY
PUBCHEM
57183875
Created by admin on Mon Mar 31 22:06:50 GMT 2025 , Edited by admin on Mon Mar 31 22:06:50 GMT 2025
PRIMARY
CAS
1246253-05-3
Created by admin on Mon Mar 31 22:06:50 GMT 2025 , Edited by admin on Mon Mar 31 22:06:50 GMT 2025
PRIMARY
SUBSTANCE RECORD
Structure of RAMIPRIL, (-)-
NIH
NCATS
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