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Details

Stereochemistry ABSOLUTE
Molecular Formula C23H32N2O5
Molecular Weight 416.5106
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of (S,R,S,S,S)-EPIMER OF RAMIPRIL

SMILES

[H][C@@]12CCC[C@]1([H])N([C@@H](C2)C(O)=O)C(=O)[C@@H](C)N[C@@H](CCC3=CC=CC=C3)C(=O)OCC

InChI

InChIKey=HDACQVRGBOVJII-HTDHLNIYSA-N
InChI=1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17+,18+,19+,20+/m1/s1

HIDE SMILES / InChI
(2S,3AS,6AS)-1-((2R)-2-(((1S)-1-(Ethoxycarbonyl)-3-phenylpropyl)amino)propanoy)octahydrocyclopenta(B)pyrrole-2-carboxylic acid is one of many isomers of ramipril and is known as Impurity I. Ramipril is an angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure (hypertension) and congestive heart failure.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
(S,R,S,S,S)-EPIMER OF RAMIPRIL
Common Name English
RAMIPRIL EPIMER, (R-METHYL)-
Common Name English
(2S,3AS,6AS)-1-((2R)-2-(((1S)-1-(ETHOXYCARBONYL)-3-PHENYLPROPYL)AMINO)PROPANOYL)OCTAHYDROCYCLOPENTA(B)PYRROLE-2-CARBOXYLIC ACID
Common Name English
CYCLOPENTA(B)PYRROLE-2-CARBOXYLIC ACID, 1-((2R)-2-(((1S)-1-(ETHOXYCARBONYL)-3-PHENYLPROPYL)AMINO)-1-OXOPROPYL)OCTAHYDRO-, (2S,3AS,6AS)-
Systematic Name English
RAMIPRIL EPIMER, (S,R,S,S,S)-
Common Name English
RAMIPRIL IMPURITY I [EP IMPURITY]
Common Name English
Code System Code Type Description
PUBCHEM
55688
Created by admin on Sat Dec 16 08:18:41 GMT 2023 , Edited by admin on Sat Dec 16 08:18:41 GMT 2023
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CAS
129939-65-7
Created by admin on Sat Dec 16 08:18:41 GMT 2023 , Edited by admin on Sat Dec 16 08:18:41 GMT 2023
PRIMARY
FDA UNII
E7CEJ08B2F
Created by admin on Sat Dec 16 08:18:41 GMT 2023 , Edited by admin on Sat Dec 16 08:18:41 GMT 2023
PRIMARY