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Showing 1 - 10 of 140 results

Status:
US Approved Rx (2015)
First approved in 2005

Class (Stereo):
CHEMICAL (ABSOLUTE)



Tigecycline (INN) is an antibiotic used to treat a number of bacterial infections. It is a first in class glycylcycline that is administered intravenously. For the treatment of infections caused by susceptible strains of the designated microorganisms...
Status:
US Approved Rx (2004)
First approved in 2004

Class (Stereo):
CHEMICAL (ACHIRAL)

Targets:


Tinidazole is a synthetic antiprotozoal agent, formally known as 1-[2-(ethylsulfonyl)ethyl]-2-methyl-5-nitroimidazole and a second-generation 2-methyl-5-nitroimidazole. Tinidazole is a prodrug and antiprotozoal agent. The nitro group of tinidazole is...
Status:
US Approved Rx (2004)
First approved in 2004

Class (Stereo):
CHEMICAL (ABSOLUTE)



Rifaximin is a structural analog of rifampin and a non-systemic, gastrointestinal site-specific antibiotic. Rifaximin acts by inhibiting bacterial ribonucleic acid (RNA) synthesis and contributes to restore intestinal microflora imbalance. It is FDA ...
Status:
US Approved Rx (2014)
First approved in 2003

Class (Stereo):
CHEMICAL (ACHIRAL)



Ibandronic acid (INN) or ibandronate sodium (USAN) is a potent bisphosphonate drug developed by Hoffman La Roche and used in the prevention and treatment of osteoporosis and metastasis-associated skeletal fractures in people with cancer. Ibandronate ...
Status:
US Approved Rx (2019)
First approved in 2001

Class (Stereo):
CHEMICAL (ABSOLUTE)



Ertapenem is a carbapenem antibiotic marketed by Merck as Invanz. The bactericidal activity of ertapenem results from the inhibition of cell wall synthesis and is mediated through ertapenem binding to penicillin binding proteins (PBPs). In Escherichi...
Status:
US Approved Rx (2002)
First approved in 2001

Class (Stereo):
CHEMICAL (ACHIRAL)



Zoledronic acid (Reclast, Aclasta, Zometa) is an intravenous, highly potent amino-bisphosphonate approved worldwide, including in the USA, EU and Japan for use in patients with primary or secondary osteoporosis or low bone mass (approved indications ...
Status:
US Approved Rx (2010)
First approved in 2000

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

Articaine is a dental local anesthetic, which is the most widely used in a number of European countries and is available in many countries around the world. Articaine in combination with epinephrine under the brand name Septocaine is indicated for lo...
Status:
US Approved Rx (2007)
First approved in 1999

Class (Stereo):
CHEMICAL (ABSOLUTE)

Targets:


Epirubicin is an anthracycline cytotoxic agent, is a 4'-epi-isomer of doxorubicin. The compound is marketed by Pfizer under the trade name Ellence in the US. It is indicated as a component of adjuvant therapy in patients with evidence of axillary nod...
Status:
US Approved Rx (2021)
First approved in 1999

Class (Stereo):
CHEMICAL (ACHIRAL)



Bexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma. Bexarotene is a member of a subclass of retinoids that selectively ...
Status:
US Approved Rx (1998)
First approved in 1998

Class (Stereo):
CHEMICAL (ABSOLUTE)



PRIFTIN® (rifapentine) is indicated in adults and children 12 years and older for the treatment of active pulmonary tuberculosis (TB) caused by Mycobacterium tuberculosis. PRIFTIN must always be used in combination with one or more antituberculosis (...