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Restrict the search for
beta carotene
to a specific field?
Status:
Investigational
Source:
NCT02622958: Phase 3 Interventional Completed Social Anxiety Disorder
(2014)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Investigational
Class (Stereo):
CHEMICAL (ABSOLUTE)
Silydianin is a flavonolignan from Silymarin, which is the major constituent of milk thistle extract. Silydianin, an active constituent of Silybium marianum, have inhibitory properties against the P2Y12 receptor and block ADP-induced blood platelet activation. Silydianin has antiinflammatory activity, it regulates caspase-3 activation, affects cell membranes and acts as a free radical scavenger. Silydianin non-competitively inhibits the lipoxygenase from soybeans in vitro. It also inhibits the formation of prostaglandins in vitro.
Class (Stereo):
CHEMICAL (RACEMIC)
Draquinolol is a cardioselective beta-adrenoceptor antagonist with a long duration of action in vivo. The long duration of action of draquinolol in vivo is due to the formation of a tight complex with beta 1-adrenoceptors. Draquinolol reduced an exercise tachycardia.
Class (Stereo):
CHEMICAL (ABSOLUTE)
Orestrate was developed as an estrogenic steroid that has never been marketed.
Status:
Investigational
Source:
INN:tafluposide [INN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Tafluposide (also known as F 11782) is an epipodophyllotoxin derivative patented by Pierre Fabre Medicament as an antitumor agent. Tafluposide acts as a catalytic inhibitor of topoisomerases I and II, that capable of completely inhibiting the DNA-binding activity of topoisomerase. In preclinical models single or multiple i.p. doses of Tafluposide proves highly active against the s.c. grafted B16 melanoma, significantly increasing survival and inhibiting tumor growth. Tafluposide inhibits the number of pulmonary metastatic foci of the melanoma by 99%. In human tumor xenograft studies, multiple i.p. doses of Tafluposide results in major inhibitory activity against breast) tumors, as well as causing definite tumor regression. Significant activity was also recorded Tafluposide against the refractory lung xenografts.
Class (Stereo):
CHEMICAL (ABSOLUTE)
Tamethicillin is a basic ester pro-drug of methicillin (MET) which is converted in the body by non-specific esterases to MET. Tamethicillin was used as an antibacterial agent in the veterinary as a useful alternative for the treatment of mastitis in livestock, especially in mastitis due to beta-lactamase-producing Staphylococcus.
Status:
Investigational
Source:
INN:tauroselcholic acid [INN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Class (Stereo):
CHEMICAL (ABSOLUTE)
Oxetacillin was developed as an antibacterial drug that has never been marketed.
Class (Stereo):
CHEMICAL (UNKNOWN)
Class (Stereo):
CHEMICAL (RACEMIC)
Penirolol is a beta-adrenergic blocking agent that was studied as an antihypertensive agent. Information about the further development of this drug is not available.
