Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C23H33N3O6S |
| Molecular Weight | 479.59 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)C3=C(OC)C=CC=C3OC)C(=O)OCCN(CC)CC
InChI
InChIKey=HBOSVRMWGCNXAB-LVCYWYKZSA-N
InChI=1S/C23H33N3O6S/c1-7-25(8-2)12-13-32-22(29)18-23(3,4)33-21-17(20(28)26(18)21)24-19(27)16-14(30-5)10-9-11-15(16)31-6/h9-11,17-18,21H,7-8,12-13H2,1-6H3,(H,24,27)/t17-,18+,21-/m1/s1
| Molecular Formula | C23H33N3O6S |
| Molecular Weight | 479.59 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Tamethicillin is a basic ester pro-drug of methicillin (MET) which is converted in the body by non-specific esterases to MET. Tamethicillin was used as an antibacterial agent in the veterinary as a useful alternative for the treatment of mastitis in livestock, especially in mastitis due to beta-lactamase-producing Staphylococcus.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Pharmacokinetic evaluation and mammary excretion of tamethicillin in the healthy goat. | 1979 Aug |
|
| Concentrations of methicillin in blood, normal milk and mastitic milk of cows after intramuscular injection of methicillin and tamethicillin. | 1983 Mar |
|
| Intramuscular treatment of subclinical staphylococcal mastitis in lactating cows with penicillin G, methicillin and their esters. | 1985 Sep |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:27:09 GMT 2023
by
admin
on
Fri Dec 15 16:27:09 GMT 2023
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| Record UNII |
11MX0V916W
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| Record Status |
Validated (UNII)
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| Record Version |
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| Name | Type | Language | ||
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Official Name | English | ||
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Common Name | English | ||
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Systematic Name | English |
| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C1500
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CHEMBL2105448
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3944
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100000083231
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DTXSID00204768
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SUB10820MIG
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11MX0V916W
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C90916
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56211-43-9
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68757
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| Related Record | Type | Details | ||
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ACTIVE MOIETY |
