U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 81 - 90 of 574 results

Status:
Investigational
Source:
USAN:DITIOCADE SODIUM [USAN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:ioglucol
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Ioglucol is a triiodoanilide derivative patented by Mallinckrodt, Inc. as nonionic -ray contrast media
Status:
Investigational
Source:
USAN:Azamethiphos
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Azamethiphos, an organothiophosphate insecticide, initially was used in 1991 for the treatment against sea lice. However, because of reduced sensitivity in 1999, the use of this compound was terminated. Azamethiphos was re-introduced in 2008; it’s the main component of Salmosan, a pesticide presently used for treatment against sea lice. Salmosan is applied as a bath treatment and then released into the surrounding seawater
Status:
Investigational
Source:
USAN:NIFLURIDIDE [USAN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Nifluridide, an experimental insecticide, is used for the control of sucking and biting insects such as Phthiraptera. Nifluridide was systemically active against Triatoma infestans on mice and Rhodnius prolixus on cattle.
Status:
Investigational
Source:
INN:furomine [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:tioctilate [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Tioctilate is a benzoic acid derivative patented by Chevron Research Co. as an acaricide and ovicide. Tioctilate is rapidly degraded by a soil extract under aerobic conditions.
Status:
Investigational
Source:
INN:galtifenin
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
USAN:SODIUM ARSENATE AS 74 [USAN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Sodium arsenate as-74 (As74) has been the principal positron-emitting scanning agent. As74 as a commercial preparation for parenteral adminitration was made available towards the end of 1956. From March 1957 all studies were made with sodium arsenate rather than sodium arsenite. Sodium arsenate as-74 was used in the diagnosis of suvatentorial brain tumours. Traces of the element were found in all body tissues, and assays of injected As74 recovered in brain tumours showed highest values in meningiomas, followed, in order, by gliolastomas, metastatic carcinomas and astrocytomas.
Status:
Investigational
Source:
INN:disofenin
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Disofenin is an iminodiacetic acid derivative with no known pharmacologic actions at the doses recommended. Technetium Tc 99m disofenin injection is a radiopharmaceutical. Technetium Tc99m disofenin is indicated as a hepatobiliary imaging agent. Technetium Tc99m disofenin is indicated in the diagnosis of acute cholecystitis as well as to rule out the occurrence of acute cholecystitis in suspected patients with right upper quadrant pain, fever, jaundice, right upper quadrant tenderness and mass or rebound tenderness, but not limited to these signs and symptoms. Itching at the site of injection progressing to erythema multiforme has been reported following single administration. Also, rare cases of chills and nausea have been reported.
Status:
Investigational
Source:
INN:quinaldine blue [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Pinacyanol iodide is a fluorescent cationic cyanine dye used to stain biological specimens. It is the obstetric diagnostic aid. The mechanism of tracing with pinacyanol iodide dyes is based on their lipid solubility. Pinacyanol iodide dyes are more efficacious than classical tracing methodologies especially during early stages of development and consequently have been used to reveal the spatiotemporal patterns of axonal development in different species. The unique properties of the pinacyanol iodide dye tracing method have opened up new avenues for tracing connections in human postmortem specimens. Pinacyanol iodide dye tracing is incompatible with alcohol fixation and paraffin embedding of tissue.