AZAMETHIPHOS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H10ClN2O5PS
Molecular Weight	324.678
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COP(=O)(OC)SCN1C(=O)OC2=C1N=CC(Cl)=C2

InChI

InChIKey=VNKBTWQZTQIWDV-UHFFFAOYSA-N

InChI=1S/C9H10ClN2O5PS/c1-15-18(14,16-2)19-5-12-8-7(17-9(12)13)3-6(10)4-11-8/h3-4H,5H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C9H10ClN2O5PS
Molecular Weight	324.678
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/27591805 | https://www.ncbi.nlm.nih.gov/pubmed/25893248

Azamethiphos, an organothiophosphate insecticide, initially was used in 1991 for the treatment against sea lice. However, because of reduced sensitivity in 1999, the use of this compound was terminated. Azamethiphos was re-introduced in 2008; it’s the main component of Salmosan, a pesticide presently used for treatment against sea lice. Salmosan is applied as a bath treatment and then released into the surrounding seawater

Approval Year

PubMed

Title	Date	PubMed
Identification and characterization of mutations in housefly (Musca domestica) acetylcholinesterase involved in insecticide resistance.	2001 Oct 1	11563981
Evidence for occurrence of an organophosphate-resistant type of acetylcholinesterase in strains of sea lice (Lepeophtheirus salmonis Krøyer).	2004 Dec	15578596
Glutathione S-transferase and insecticide resistance in laboratory strains and field populations of Musca domestica.	2005 Aug	16156589
Differential protein adduction by seven organophosphorus pesticides in both brain and thymus.	2007 Apr	17615116
Potential role of cholinesterases in the invasive capacity of the freshwater bivalve, Anodonta woodiana (Bivalvia: Unionacea): a comparative study with the indigenous species of the genus, Anodonta sp.	2007 Apr	17324630
Cholinesterase activities in the scallop Pecten jacobaeus: characterization and effects of exposure to aquatic contaminants.	2008 Mar 15	18177688

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:38:58 GMT 2023` Edited by `admin` on `Fri Dec 15 15:38:58 GMT 2023`
Record UNII	9440R8149U
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

AZAMETHIPHOS

Common Name

English

AZAMETHIPHOS [MI]

Common Name

English

AZAMETHIPHOS [MART.]

Common Name

English

S-((6-CHLORO-2,3-DIHYDRO-2-OXO-1,3-OXAZOLO-(4,5-B)PYRIDIN-3-YL)METHYL) O,O-DIMETHYL PHOSPHOROTHIOATE.

Common Name

English

OMS NO 1825

Code

English

S-((6-CHLORO-2-OXOOXAZOLO(4,5-B)PYRIDIN-3(2H)-YL)METHYL) O,O-DIMETHYL PHOSPHOROTHIOATE

Systematic Name

English

S-6-CHLORO-2,3-DIHYDRO-2-OXO-1,3-OXAZOLO(4,5-B)PYRIDIN-3-YLMETHYL O,O-DIMETHYL PHOSPHOROTHIOATE

Systematic Name

English

CGA 18809

Code

English

OMS-NO-1825

Code

English

CGA-18809

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C737