NIFLURIDIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H6F7N3O3
Molecular Weight	349.1618
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=C(NC(=O)C(F)(F)C(F)F)C=C(C=C1[N+]([O-])=O)C(F)(F)F

InChI

InChIKey=YUANPWFOQAEKNA-UHFFFAOYSA-N

InChI=1S/C10H6F7N3O3/c11-7(12)9(13,14)8(21)19-4-1-3(10(15,16)17)2-5(6(4)18)20(22)23/h1-2,7H,18H2,(H,19,21)

HIDE SMILES / InChI

Molecular Formula	C10H6F7N3O3
Molecular Weight	349.1618
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6815915 | https://www.ncbi.nlm.nih.gov/pubmed/6891855 | https://sitem.herts.ac.uk/aeru/vsdb/Reports/2554.htm

Nifluridide, an experimental insecticide, is used for the control of sucking and biting insects such as Phthiraptera. Nifluridide was systemically active against Triatoma infestans on mice and Rhodnius prolixus on cattle.

Approval Year

PubMed

Title	Date	PubMed
The activity of nifluridide on reduviids and rodent and human trypanosomes.	1982	6815915
Automated extraction technique for determination of experimental insecticide nifluridide and its cyclized product in water by high pressure liquid chromatography.	1983 Jan	6681812
Red imported fire ants (Hymenoptera: Formicidae): population dynamics following treatment with insecticidal baits.	1985 Aug	4056198

Patents

Sample Use Guides

In Vivo Use Guide

The ability of nifluridide to kill reduviids was assayed in mice fed 7 ppm in diet and on cattle injected subcutaneously at 5 mg/kg body weight.

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:34:31 GMT 2023` Edited by `admin` on `Fri Dec 15 15:34:31 GMT 2023`
Record UNII	849K45OH8R
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NIFLURIDIDE

Official Name

English

NIFLURIDIDE [USAN]

Common Name

English

6'-AMINO-.ALPHA.,.ALPHA.,.ALPHA.,2,2,3,3-HEPTAFLUORO-5'-NITRO-M-PROPIONOTOLUIDIDE

Common Name

English

6'-AMINO-.ALPHA.,.ALPHA.,.ALPHA.,2,2,3,3-HEPTAFLUORO-5'-NITROPROPION-M-TOLUIDIDE

Common Name

English

COMPOUND 109168

Code

English

PROPANAMIDE, N-(2-AMINO-3-NITRO-5-(TRIFLUOROMETHYL)PHENYL)-2,2,3,3-TETRAFLUORO-

Systematic Name

English

N-(2-AMINO-3-NITRO-5-(TRIFLUOROMETHYL)PHENYL)-2,2,3,3-TETRAFLUOROPROPANAMIDE

Systematic Name

English

COMPOUND-109168

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C737