Flamenol (3,5-Dihydroxyanisole) is organic compound used in synthesis of isorobustin and substituted linear and angular benzofurocoumarins

FLEROBUTEROL is a beta-adrenoceptor agonist with potential antidepressant activity.

Succisulfone is a sulfonamide derivative patented by Antoine Mouneyrat as antibiotic useful in the treatment of leprosy

Tiotidine is a controversial histamine H2 receptor ligand with negligible activity against H1- and H3- receptors. It was found that tiotidine behaves as an inverse agonist in U-937 cells, diminishing basal cAMP levels. Tiotidine showed two binding sites, one with high affinity and low capacity and the other with low affinity and high capacity. Tiotidine is currently in use as a radioligand in histamine H2-receptor binding studies. Compared to cimetidine, tiotidine appears to be approximately eight times more potent on a molar basis than cimetidine as an inhibitor of acid secretion, and the tiotidine effect is more prolonged. It was developed for the treatment of peptic ulcer.

Gapicomine is a coronary vasodilator, developed in Poland. It has been withdrawn from the market in the countries it was used in. Gapicomine is a major component in the drug Bicordin.

Pendecamaine, a zwitterionic agent that was used as an ampholytic surface-active agent in surgical scrubs and in cosmetic and toilet preparations. Information about the current use of this drug is not available.

Phthalylsulfamethizole is the sulfonamide. It was used as an antibacterial agent.

Sonepiprazole exhibits highly specific binding to the D4 dopamine receptor with more than 100-fold selectivity for the D4 receptor over other receptors, including dopamine, serotonin, and adrenergic receptors. It is a neutral antagonist at the D4 dopamine receptor and is devoid of dopamine agonist activity. Sonepiprazole selectively induces c-fos expression in the prefrontal cortex and blocks behavioral, biochemical, and genomic effects of repeated amphetamine administration in rats. Sonepiprazole was investigated as an antipsychotic for the treatment of schizophrenia in a placebo-controlled clinical trial, but in contrast to its comparator olanzapine no benefits were found and it was not researched further for this indication.

Piclonidine is imidazoline derivative. Piclonidine has a relative specificity for the hypotensive action and thus indicate that the compound differs from the chemical congener clonidine which has other pharmacological effects involving several peripheral or centrally regulated autonomic functions. Unlike clonidine, this chemically related compound did not evoke hypertensive episodes or cause sedation in animals up to the oral dose of 1 mg/kg.

Ocaperidone [R 79598] is an equipotent antagonist of central dopamine D2 and serotonin2 receptors being investigated as a potential antipsychotic agent. Ocaperidone is a benzisoxazol piperidine antipsychotic primarily binds and with high affinity to 5-HT2 (serotonin) receptors, alpha1 and alpha 2 adrenergic receptors, dopamine D2 receptors and histamine H1 receptors. Ocaperidone is an antagonist primarily at the 5HT and D2 receptors. A proposed mechanism of action is the central D2 receptor blockade which is common to all neuroleptics that are used to treat positive symptoms of schizophrenia.