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Details

Stereochemistry RACEMIC
Molecular Formula C12H18FNO
Molecular Weight 211.2758
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FLEROBUTEROL

SMILES

CC(C)(C)NCC(O)C1=C(F)C=CC=C1

InChI

InChIKey=XTJMTDZHCLBKFU-UHFFFAOYSA-N
InChI=1S/C12H18FNO/c1-12(2,3)14-8-11(15)9-6-4-5-7-10(9)13/h4-7,11,14-15H,8H2,1-3H3

HIDE SMILES / InChI

Description

FLEROBUTEROL is a beta-adrenoceptor agonist with potential antidepressant activity.

CNS Activity

CNS Active
3913
Curator's Comment: Known to be CNS active in rat. Human data not available.

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
Effects of CRL 40827 and salbutamol on exocrine pancreatic secretion in rats.
1988 Jan 27
Patents

Patents

JPS60126251A
6

Sample Use Guides

In Vitro Use Guide
Flerobuterol is a beta1- and beta2-adrenoceptor agonist (Ki = 926 nM and 518 nM, respectively).
Name Type Language
FLEROBUTEROL
INN  
INN  
Official Name English
.ALPHA.-((TERT-BUTYLAMINO)METHYL)-O-FLUOROBENZYL ALCOHOL
Common Name English
BENZENEMETHANOL, .ALPHA.-(((1,1-DIMETHYLETHYL)AMINO)METHYL)-2-FLUORO-
Systematic Name English
flerobuterol [INN]
Common Name English
2-(TERT-BUTYLAMINO)-1-(2-FLUOROPHENYL)ETHAN-1-OL
Common Name English
(±)-FLEROBUTEROL
Common Name English
.ALPHA.-(((1,1-DIMETHYLETHYL)AMINO)METHYL)-2-FLUOROBENZENEMETHANOL
Common Name English
DL-FLEROBUTEROL
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C265
Created by admin on Fri Dec 15 15:50:52 GMT 2023 , Edited by admin on Fri Dec 15 15:50:52 GMT 2023
NCI_THESAURUS C48149
Created by admin on Fri Dec 15 15:50:52 GMT 2023 , Edited by admin on Fri Dec 15 15:50:52 GMT 2023
Code System Code Type Description
EPA CompTox
DTXSID80868640
Created by admin on Fri Dec 15 15:50:52 GMT 2023 , Edited by admin on Fri Dec 15 15:50:52 GMT 2023
PRIMARY
CAS
82101-10-8
Created by admin on Fri Dec 15 15:50:52 GMT 2023 , Edited by admin on Fri Dec 15 15:50:52 GMT 2023
PRIMARY
CAS
101687-92-7
Created by admin on Fri Dec 15 15:50:52 GMT 2023 , Edited by admin on Fri Dec 15 15:50:52 GMT 2023
SUPERSEDED
ChEMBL
CHEMBL2106772
Created by admin on Fri Dec 15 15:50:52 GMT 2023 , Edited by admin on Fri Dec 15 15:50:52 GMT 2023
PRIMARY
FDA UNII
F05RR5M463
Created by admin on Fri Dec 15 15:50:52 GMT 2023 , Edited by admin on Fri Dec 15 15:50:52 GMT 2023
PRIMARY
SMS_ID
100000080991
Created by admin on Fri Dec 15 15:50:52 GMT 2023 , Edited by admin on Fri Dec 15 15:50:52 GMT 2023
PRIMARY
PUBCHEM
71254
Created by admin on Fri Dec 15 15:50:52 GMT 2023 , Edited by admin on Fri Dec 15 15:50:52 GMT 2023
PRIMARY
INN
6130
Created by admin on Fri Dec 15 15:50:52 GMT 2023 , Edited by admin on Fri Dec 15 15:50:52 GMT 2023
PRIMARY
MESH
C071321
Created by admin on Fri Dec 15 15:50:52 GMT 2023 , Edited by admin on Fri Dec 15 15:50:52 GMT 2023
PRIMARY
EVMPD
SUB07638MIG
Created by admin on Fri Dec 15 15:50:52 GMT 2023 , Edited by admin on Fri Dec 15 15:50:52 GMT 2023
PRIMARY
NCI_THESAURUS
C65691
Created by admin on Fri Dec 15 15:50:52 GMT 2023 , Edited by admin on Fri Dec 15 15:50:52 GMT 2023
PRIMARY
ACTIVE MOIETY
Structure of FLEROBUTEROL
SALT/SOLVATE (PARENT)
Structure of FLEROBUTEROL HYDROCHLORIDE
NIH
NCATS
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