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Showing 61 - 70 of 804 results

Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)



Alvameline is a partial agonist of the M1 mAChR that also displays M2/M3 antagonist effects. It readily crosses the blood-brain barrier. It has an effect profile that makes it of interest to test its ability to counteract bladder overactivity in huma...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)



ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine] is a potent cholinergic neuronal nicotinic acetylcholine receptor (nAChR) ligand with analgesic properties. ABT-594 binds alpha-4/ beta-2 neuronal nAChRs acting as an agonist. ABT-594 is studying...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)


Dianicline binds with high affinity to the rat and human alpha4beta2 nicotinic acetylcholine receptor (nAChR) subtypes and displays selectivity for the alpha4beta2 nAChR. Electrophysiological experiments indicate that dianicline is a partial agonist ...
Status:
Investigational

Class (Stereo):
CHEMICAL (RACEMIC)



ANAVEX 2-73 is an orally available drug candidate developed to potentially modify Alzheimer’s. This drug is in Phase II trials for Alzheimer's disease and Rett syndrome, phase I trials for epilepsy and in preclinical trials for multiple sclerosis and...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)


Tarafenacin (also known as SVT-40776) was developed as muscarinic M3 receptor antagonist for the treatment of overactive bladder. The drug participated in phase II clinical trial in patients suffering from overactive bladder, where both dose levels o...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)