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Showing 51 - 60 of 804 results

Status:
US Approved OTC
First approved in 1948

Class (Stereo):
CHEMICAL (RACEMIC)



Doxylamine is an antihistamine commonly used as a sleep aid. This drug is also used to relieve symptoms of hay fever (allergic rhinitis), hives (rash or itching), and other allergic reactions. Doxylamine is a member of the ethanolamine class of antih...
Status:
US Approved OTC
First approved in 1946

Class (Stereo):
CHEMICAL (ACHIRAL)



Diphenhydramine is an antihistamine which is used in the combination with naproxen sodium for the relief of occasional sleeplessness when associated with minor aches and pains. Diphenhydramine has a role nighttime sleep-aid and naproxen sodium is a p...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)

Sofinicline is a selective agonist of the a4b2 subtype of nAChR. It is under development by Abbott Laboratories in collaboration with NeuroSearch. It is produced as a capsule in doses of 1, 2 or 4 mg. Sofinicline is a full agonist of the a4b2 nAChR. ...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)



Xanomeline (LY-246,708) is an orthosteric muscarinic acetylcholine receptor (mAChR) agonist, often referred to as M1/M4-preferring. It is also known to act as a M5 receptor antagonist. Xanomeline was studied in clinical trials phase I in schizophreni...
Status:
Investigational

Class (Stereo):
CHEMICAL (RACEMIC)


Meletimide (R 5183) is a powerful anticholinergic agent with pronounced peripheral and central action.
Status:
Investigational

Class (Stereo):
CHEMICAL (RACEMIC)



Atropine-N-oxide hydrochloride is an alkaloid of the belladonna plants. It is the major metabolite of atropine. It is a competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)



Altinicline (SIB-1508Y, SIB-1765F) is a drug which acts as an agonist at neural nicotinic acetylcholine receptors with high selectivity for the α4β2 subtype. It stimulates release of dopamine and acetylcholine in the brain in both rodent and primate ...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)



Pozanicline is an alpha4-beta2 neuronal nicotinic receptor partial agonist. It had been in phase II clinical trials for the treatment of attention hyperactivity disorder and Alzheimer’s disease. It was tested for the treatment of schizophrenia too. A...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)

Revatropate is a muscarinic antagonist with selectivity for M1 and M3 receptor subtypes. Significant improvement in airway function was shown in horses with heaves after inhalation of revatropate, and it was found to be a safe and effective bronchodi...