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Details

Stereochemistry ABSOLUTE
Molecular Formula C19H27NO4S
Molecular Weight 365.487
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of REVATROPATE

SMILES

C[S@@+]([O-])CC[C@](CO)(C(=O)O[C@H]1CN2CCC1CC2)C3=CC=CC=C3

InChI

InChIKey=VGXACJMXDYPFDB-SXMMONRFSA-N
InChI=1S/C19H27NO4S/c1-25(23)12-9-19(14-21,16-5-3-2-4-6-16)18(22)24-17-13-20-10-7-15(17)8-11-20/h2-6,15,17,21H,7-14H2,1H3/t17-,19+,25+/m0/s1

HIDE SMILES / InChI
Revatropate is a muscarinic antagonist with selectivity for M1 and M3 receptor subtypes. Significant improvement in airway function was shown in horses with heaves after inhalation of revatropate, and it was found to be a safe and effective bronchodilator. Early clinical studies in chronic obstructive airway disease (COAD) patients also showed that inhaled revatropate was an effective bronchodilator, and well tolerated.

Originator

Approval Year

Name Type Language
REVATROPATE
INN  
INN  
Official Name English
UK-112,166
Code English
BENZENEACETIC ACID, .ALPHA.-(HYDROXYMETHYL)-.ALPHA.-(2-(METHYLSULFINYL)ETHYL)-, 1-AZABICYCLO(2.2.2)OCT-3-YL ESTER, (3R-(3R*(S*(R*))))-
Systematic Name English
UK-112166
Code English
BENZENEACETIC ACID, .ALPHA.-(HYDROXYMETHYL)-.ALPHA.-(2-((R)-METHYLSULFINYL)ETHYL)-, (3R)-1-AZABICYCLO(2.2.2)OCT-3-YL ESTER, (.ALPHA.S)-
Systematic Name English
revatropate [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29704
Created by admin on Sat Dec 16 16:32:12 GMT 2023 , Edited by admin on Sat Dec 16 16:32:12 GMT 2023
Code System Code Type Description
SMS_ID
100000080574
Created by admin on Sat Dec 16 16:32:12 GMT 2023 , Edited by admin on Sat Dec 16 16:32:12 GMT 2023
PRIMARY
FDA UNII
3W7L15V40W
Created by admin on Sat Dec 16 16:32:12 GMT 2023 , Edited by admin on Sat Dec 16 16:32:12 GMT 2023
PRIMARY
PUBCHEM
9554797
Created by admin on Sat Dec 16 16:32:12 GMT 2023 , Edited by admin on Sat Dec 16 16:32:12 GMT 2023
PRIMARY
EVMPD
SUB10293MIG
Created by admin on Sat Dec 16 16:32:12 GMT 2023 , Edited by admin on Sat Dec 16 16:32:12 GMT 2023
PRIMARY
ChEMBL
CHEMBL2105235
Created by admin on Sat Dec 16 16:32:12 GMT 2023 , Edited by admin on Sat Dec 16 16:32:12 GMT 2023
PRIMARY
NCI_THESAURUS
C75283
Created by admin on Sat Dec 16 16:32:12 GMT 2023 , Edited by admin on Sat Dec 16 16:32:12 GMT 2023
PRIMARY
MESH
C105222
Created by admin on Sat Dec 16 16:32:12 GMT 2023 , Edited by admin on Sat Dec 16 16:32:12 GMT 2023
PRIMARY
INN
7425
Created by admin on Sat Dec 16 16:32:12 GMT 2023 , Edited by admin on Sat Dec 16 16:32:12 GMT 2023
PRIMARY
CAS
149926-91-0
Created by admin on Sat Dec 16 16:32:12 GMT 2023 , Edited by admin on Sat Dec 16 16:32:12 GMT 2023
PRIMARY